Area of research
Radiology, Nuclear Medicine and Imaging · Cellular and Molecular Neuroscience
Research interest
Qi-Huang Zheng, Ph.D. is an Associate Professor of Radiology and Imaging Sciences with tenure in the Department of Radiology and Imaging Sciences at Indiana University School of Medicine. His expertise ranges from synthetic organic chemistry/natural product chemistry to radiopharmaceutical chemistry/molecular imaging science with a focus on positron emission tomography (PET) radiochemistry. His current research interests are design, synthesis and biological evaluation of new radiopharmaceuticals (tumor, brain and heart imaging agents) for use in the biomedical imaging technique PET to study cancer, neuroscience and cardiovascular diseases. His research activities focus on the development of novel and potent enzyme-, receptor- and transporter-based PET carbon-11 and fluorine-18 radiotracers for the qualitative and quantitative assessment of physiologic changes in vivo, from initial evaluation in cell and animal models to evaluation in clinical trials. His research activities also include development, automation and production of PET radiotracers for preclinical and clinical imaging applications. He has received various honors and awards such as China Young Chemist Prize in 1991; China Guangdong Province Outstanding Teacher Award in 1992, China Guangdong Province Science and Technology Progress Achievement Award in 1995; One of the Top Ten Authors for Radiology Publications at Indiana University School of Medicine in 2008, 2009, 2010; Bioorganic & Medicinal Chemistry Letters Most Cited Paper 2006-2009 Award in 2009; and Bioorganic & Medicinal Chemistry Letters, Bioorganic & Medicinal Chemistry, European Journal of Medicinal Chemistry, and Journal of Neuroimmunology Outstanding Reviewer Award in 2015, 2016, 2017, 2018. He is serving as a Senior Editorial/Editorial Board Member in numerous scientific journals, an abstract reviewer for the Society of Nuclear Medicine and Molecular Imaging (SNMMI) Annual Meeting, a manuscript reviewer for more than 80 scientific journals
A carbon-11 labeled imidazo[1,2- a ]pyridine derivative as a new potential PET probe targeting PI3K/mTOR in cancer. Li W, Ma W, Wang M, Wang Z, Grega SD, Zheng QH , Xu Z. Am J Nucl Med Mol Imaging. 2023 Jun 25;13(3):95-106. eCollection 2023. PMID: 37457324
— 2023cited by 0position: selected
Imaging ligands targeting glypican-3 receptor expression in hepatocellular carcinoma. Grega SD, Zheng DX, Zheng QH . Am J Nucl Med Mol Imaging. 2022 Aug 20;12(4):113-121. eCollection 2022. PMID: 36072763
— 2022cited by 0position: selected