Area of research
Surgery · Cancer Research
Research interest
Research interests include Esophageal Cancer Research and Treatment, Cancer Genomics and Diagnostics, Gastric Cancer Management and Outcomes, and Histone Deacetylase Inhibitors Research.
Integrated epidemiological and molecular data inform the relationship between precancer and cancer states of esophageal adenocarcinoma
Context-dependent effects of CDKN2A and other 9p21 gene losses during the evolution of esophageal cancer
Disentangling oncogenic amplicons in esophageal adenocarcinoma
Trimodality therapy versus perioperative chemotherapy in the management of locally advanced adenocarcinoma of the oesophagus and oesophagogastric junction (Neo-AEGIS): an open-label, randomised, phase 3 trial
Mutational signature dynamics shaping the evolution of oesophageal adenocarcinoma
A decade of the Oesophageal Cancer Clinical and Molecular Stratification Consortium
Phosphodiesterase type 5 inhibitors enhance chemotherapy in preclinical models of esophageal adenocarcinoma by targeting cancer-associated fibroblasts
Risk Prediction Model of 90-Day Mortality After Esophagectomy for Cancer
Outcomes after totally minimally invasive <i>versus</i> hybrid and open Ivor Lewis oesophagectomy: results from the International Esodata Study Group
Modulation of the Tumor Promoting Functions of Cancer Associated Fibroblasts by Phosphodiesterase Type 5 Inhibition Increases the Efficacy of Chemotherapy in Human Preclinical Models of Esophageal Adenocarcinoma
Modulation of the tumour promoting functions of cancer associated fibroblasts by phosphodiesterase type 5 inhibition increases the efficacy of chemotherapy in human preclinical models of esophageal adenocarcinoma
Modulation of the tumour promoting functions of cancer associated fibroblasts by phosphodiesterase type 5 inhibition increases the efficacy of chemotherapy in human preclinical models of esophageal adenocarcinoma
Identification of Subtypes of Barrett’s Esophagus and Esophageal Adenocarcinoma Based on DNA Methylation Profiles and Integration of Transcriptome and Genome Data
Patient-specific cancer genes contribute to recurrently perturbed pathways and establish therapeutic vulnerabilities in esophageal adenocarcinoma
Multicentre cohort study to define and validate pathological assessment of response to neoadjuvant therapy in oesophagogastric adenocarcinoma
Whole-genome sequencing provides new insights into the clonal architecture of Barrett's esophagus and esophageal adenocarcinoma
British Society of Gastroenterology guidelines on the diagnosis and management of Barrett's oesophagus