John J. Flanagan

Area of research

Physiology · Rheumatology

Research interest

Research focused on Pharmacology and Gene knockdown, with related work in Synucleinopathies, Fabry disease, Ubiquitin. Notable publications include 'Catalytic in vivo protein knockdown by small-molecule PROTACs', 'A GCase Chaperone Improves Motor Function in a Mouse Model of Synucleinopathy', and 'Oral Migalastat HCl Leads to Greater Systemic Exposure and Tissue Levels of Active α-Galactosidase A in Fabry Patients when Co-Administered with Infused Agalsidase'.

h-index

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citations

1,503

works

NIH funding

—

primary concept

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Recent publications

Duvoglustat HCl Increases Systemic and Tissue Exposure of Active Acid α-Glucosidase in Pompe Patients Co-administered with Alglucosidase α

Molecular Therapy 2017cited by 44position: middledoi

Catalytic in vivo protein knockdown by small-molecule PROTACs

Nature Chemical Biology 2015cited by 1,291position: middledoi

Oral Migalastat HCl Leads to Greater Systemic Exposure and Tissue Levels of Active α-Galactosidase A in Fabry Patients when Co-Administered with Infused Agalsidase

PLoS ONE 2015cited by 62position: middledoi

A GCase Chaperone Improves Motor Function in a Mouse Model of Synucleinopathy

Neurotherapeutics 2014cited by 106position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

— · 2 papers (2014–2015)— · 2 papers (2014–2015)— · 2 papers (2014–2015)— · 1 papers (2014–2014)— · 1 papers (2015–2015)— · 1 papers (2015–2015)Vincent Lemesre · University of California, Los Angeles1 papers (2014–2014)Chunni Zhu · University of California, Los Angeles1 papers (2014–2014)Marie‐Françoise Chesselet · University of California, Los Angeles1 papers (2014–2014)— · 1 papers (2015–2015)Pedrom C. Sioshansi · Michigan Ear Institute1 papers (2014–2014)Krystal De La Rosa · University of California, Los Angeles1 papers (2014–2014)— · 1 papers (2014–2014)Suma P. Shankar · University of California Davis Medical Center1 papers (2015–2015)— · 1 papers (2015–2015)David G. Warnock · University of Alabama at Birmingham1 papers (2015–2015)Sindalana Hean · Torrance Memorial Medical Center1 papers (2014–2014)— · 1 papers (2015–2015)Farzad Mortazavi · Boston University1 papers (2014–2014)Melanie B. Watson · University of California, Los Angeles1 papers (2014–2014)