Area of research
Rheumatology · Immunology
Research interest
Research focused on Human leukocyte antigen and Genetics, with related work in Genome-wide association study, Allele, Single-nucleotide polymorphism. Notable publications include 'Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome', 'Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as Susceptibility Loci for Systemic Lupus Erythematosus in a Large-Scale Multiracial Replication Study', and 'Unraveling Multiple MHC Gene Associations with Systemic Lupus Erythematosus: Model Choice Indicates a Role for HLA Alleles and Non-HLA Genes in Europeans'.
Utility of Candidate Genes From an Algorithm Designed to Predict Genetic Risk for Opioid Use Disorder
Latent autoimmunity across disease-specific boundaries in at-risk first-degree relatives of SLE and RA patients
Genetic fine mapping of systemic lupus erythematosus MHC associations in Europeans and African Americans
Genetic variants at the 16p13 locus confer risk for eosinophilic esophagitis
A plausibly causal functional lupus-associated risk variant in the STAT1–STAT4 locus
Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons
Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity
Klinefelter's syndrome (47,XXY) is in excess among men with Sjögren's syndrome
Decreased SMG7 expression associates with lupus-risk variants and elevated antinuclear antibody production
Genome‐Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture
Lupus Risk Variant Increases pSTAT1 Binding and Decreases ETS1 Expression
Genetic association of CD247 (CD3ζ) with SLE in a large-scale multiethnic study
The IRF5–TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share
Genetic analysis of the pathogenic molecular sub-phenotype interferon-alpha identifies multiple novel loci involved in systemic lupus erythematosus
Preferential association of a functional variant in complement receptor 2 with antibodies to double-stranded DNA
Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome
MicroRNA-3148 Modulates Allelic Expression of Toll-Like Receptor 7 Variant Associated with Systemic Lupus Erythematosus
Allelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations
PTPN22 Association in Systemic Lupus Erythematosus (SLE) with Respect to Individual Ancestry and Clinical Sub-Phenotypes
Trans-Ancestral Studies Fine Map the SLE-Susceptibility Locus TNFSF4
Preferential Binding to Elk-1 by SLE-Associated IL10 Risk Allele Upregulates IL10 Expression
Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as Susceptibility Loci for Systemic Lupus Erythematosus in a Large-Scale Multiracial Replication Study
Unraveling Multiple MHC Gene Associations with Systemic Lupus Erythematosus: Model Choice Indicates a Role for HLA Alleles and Non-HLA Genes in Europeans
Genome-Wide Association Study of African and European Americans Implicates Multiple Shared and Ethnic Specific Loci in Sarcoidosis Susceptibility
Fine mapping of Xq28: both MECP2 and IRAK1 contribute to risk for systemic lupus erythematosus in multiple ancestral groups
Impact of genetic ancestry and sociodemographic status on the clinical expression of systemic lupus erythematosus in American Indian–European populations
Association of two independent functional risk haplotypes in <i>TNIP1</i> with systemic lupus erythematosus
Variation in the ICAM1–ICAM4–ICAM5 locus is associated with systemic lupus erythematosus susceptibility in multiple ancestries
A functional haplotype of UBE2L3 confers risk for systemic lupus erythematosus
Evaluation of <i>TRAF6</i> in a large multiancestral lupus cohort