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Karl S. Peggs

CRUK Lung Cancer Centre of Excellence · GB
Area of research
Oncology · Hematology
Research interest
Research interests include CAR-T cell therapy research, Hematopoietic Stem Cell Transplantation, Cytomegalovirus and herpesvirus research, and Immune Cell Function and Interaction.
h-index
84
citations
32,712
works
423
NIH funding
primary concept
Medicine
email

Recent publications

Matched donor allogeneic CAR-T for adult B-ALL: toxicity, efficacy, repeat dosing, and the importance of lymphodepletion
Blood 2025cited by 8position: lastdoi
Comparative Emergence of Maribavir and Ganciclovir Resistance in a Randomized Phase 3 Clinical Trial for Treatment of Cytomegalovirus Infection
The Journal of Infectious Diseases 2024cited by 25position: middledoi
The evolution of lung cancer and impact of subclonal selection in TRACERx
Nature 2023cited by 300position: middledoi
The evolution of non-small cell lung cancer metastases in TRACERx
Nature 2023cited by 230position: middledoi
Dual targeting of CD19 and CD22 with Bicistronic CAR-T cells in Patients with Relapsed/Refractory Large B Cell Lymphoma
Blood 2023cited by 69position: middledoi
Treatment for First Cytomegalovirus Infection Post–Hematopoietic Cell Transplant in the AURORA Trial: A Multicenter, Double-Blind, Randomized, Phase 3 Trial Comparing Maribavir With Valganciclovir
Clinical Infectious Diseases 2023cited by 52position: middledoi
Durable Responses and Low Toxicity After Fast Off-Rate CD19 Chimeric Antigen Receptor-T Therapy in Adults With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia
Journal of Clinical Oncology 2021cited by 138position: lastdoi
Cytomegalovirus (CMV) Cell-Mediated Immunity and CMV Infection After Allogeneic Hematopoietic Cell Transplantation: The REACT Study
Clinical Infectious Diseases 2020cited by 108position: middledoi
The T cell differentiation landscape is shaped by tumour mutations in lung cancer
Nature Cancer 2020cited by 102position: middledoi
Publisher Correction: Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse
Nature Medicine 2020cited by 3position: middledoi
Publisher Correction: Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer
Nature Medicine 2020cited by 1position: middledoi
ASTCT Consensus Grading for Cytokine Release Syndrome and Neurologic Toxicity Associated with Immune Effector Cells
Biology of Blood and Marrow Transplantation 2018cited by 3,348position: middledoi
Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution
Nature 2017cited by 1,872position: middledoi
Use of Viral Load as a Surrogate Marker in Clinical Studies of Cytomegalovirus in Solid Organ Transplantation: A Systematic Review and Meta-analysis
Clinical Infectious Diseases 2017cited by 95position: middledoi
Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade
Science 2016cited by 3,084position: middledoi
Guidelines for the management of diffuse large B‐cell lymphoma
British Journal of Haematology 2016cited by 166position: lastdoi
Diagnosis of Neuroinvasive Astrovirus Infection in an Immunocompromised Adult With Encephalitis by Unbiased Next-Generation Sequencing
Clinical Infectious Diseases 2015cited by 304position: middledoi
Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti–CTLA-4 therapy against melanoma
The Journal of Experimental Medicine 2013cited by 1,443position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Robin K. Avery · Atotech (United States)2 papers (2020–2024)Drew J. Winston · University of California, Los Angeles2 papers (2020–2024)Lynn El Haddad · University of Florida1 papers (2020–2020)Sridhar Chaganti · University Hospitals Birmingham NHS Foundation Trust1 papers (2016–2016) · 1 papers (2020–2020)Bianca Santomasso · United States Fish and Wildlife Service1 papers (2018–2018)Ella Ariza‐Heredia · The University of Texas MD Anderson Cancer Center1 papers (2020–2020)Marcel R.M. van den Brink · Beckman Research Institute1 papers (2018–2018)Jeffrey V. Ravetch · Rockefeller University1 papers (2013–2013)Ying Jiang · Xinjiang Medical University1 papers (2020–2020)Rahul Phadke · Great Ormond Street Hospital1 papers (2015–2015)Kathleen M Mulane · University of Illinois Chicago1 papers (2020–2020)Sergio A. Quezada · Cancer Research UK1 papers (2013–2013)Kim Linton · Cancer Research UK Manchester Institute1 papers (2016–2016)Claire Roddie · Cancer Institute (WIA)1 papers (2013–2013)Pam McKay · Semmelweis University1 papers (2016–2016)Kate Cwynarski · University College Hospital1 papers (2016–2016)Tyler R. Simpson · Bristol-Myers Squibb (United States)1 papers (2013–2013)Frederick L. Locke · Moffitt Cancer Center1 papers (2018–2018)Andrew McMillan · Nottingham University Hospitals NHS Trust1 papers (2016–2016)