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Hongbo Guo

University of Toronto · CA
Area of research
Cancer Research · Pulmonary and Respiratory Medicine
Research interest
Research interests include MicroRNA in disease regulation, Lung Cancer Research Studies, Lung Cancer Diagnosis and Treatment, and Lung Cancer Treatments and Mutations.
h-index
43
citations
10,672
works
157
NIH funding
primary concept
email

Recent publications

Integrative Multi-Omics Analysis Reveals the Characteristic Metabolic Signature of Glioma and Enables Plasma-Based Liquid Biopsy.
2026cited by 0position: contributordoi
Pharmacological Induction of Mitochondria-Lysosome Hyper-Tethering Elicits Synthetic Lethality in Glioblastoma
2026cited by 0position: contributordoi
Pharmacological Induction of Mitochondria-Lysosome Hyper-Tethering Elicits Synthetic Lethality in Glioblastoma
Cancer Letters 2026cited by 0position: contributordoi
Ligand interaction landscape of transcription factors and essential enzymes in E. coli
Cell 2025cited by 11position: middledoi
ALKBH5 facilitates tumor progression via an m6A-YTHDC1-dependent mechanism in glioma.
2025cited by 6position: contributordoi
Isovalerylspiramycin I Reprograms the Immunosuppressive and Temozolomide-Resistant Microenvironment by Inhibiting the Frizzled-5/Wnt/β-Catenin Pathway in Glioblastoma.
2025cited by 1position: contributordoi
Immunological and pathological characteristics of brain parenchymal and leptomeningeal metastases from non-small cell lung cancer.
2025cited by 1position: contributordoi
Glial changes and gene expression in Alzheimer's disease from snRNA-Seq and spatial transcriptomics.
2025cited by 0position: contributordoi
Histone H3K9 Lactylation Confers Temozolomide Resistance in Glioblastoma via LUC7L2-Mediated MLH1 Intron Retention.
2024cited by 76position: contributordoi
The effect of aperiodic components in distinguishing Alzheimer's disease from frontotemporal dementia.
2024cited by 28position: contributordoi
Framework nucleic acid-based nanoparticles enhance temozolomide sensitivity in glioblastoma.
2024cited by 25position: contributordoi
InN@In2S3 Core-Shell nanorod for oxygen-free and penetration depth-unrestricted photodynamic therapy against glioblastoma
Chemical Engineering Journal 2024cited by 4position: contributordoi
IL-18, a therapeutic target for immunotherapy boosting, promotes temozolomide chemoresistance via the PI3K/AKT pathway in glioma.
2024cited by 1position: contributordoi
Corrigendum to "Adiponectin attenuates neuronal apoptosis induced by hypoxia-ischemia via the activation of AdipoR1/APPL1/LKB1/AMPK pathway in neonatal rats" [Neuropharmacology 133 (2018) 415-428/NP_7092].
2024cited by 0position: contributordoi
IL-18, a therapeutic target for immunotherapy boosting, promotes temozolomide chemoresistance via the PI3K/AKT pathway in glioma
2024cited by 0position: contributordoi
Polyhedral Oligomeric Silsesquioxane-Based Nanoparticles for Efficient Chemotherapy of Glioblastoma.
2023cited by 15position: contributordoi
IRP1 mediated ferroptosis reverses temozolomide resistance in glioblastoma via affecting LCN2/FPN1 signaling axis depended on NFKB2.
2023cited by 10position: contributordoi
The effect of aperiodic components in distinguishing Alzheimer's disease from frontotemporal dementia
2023cited by 1position: contributordoi
Associations of Healthy Lifestyles with All-Cause Mortality Among Individuals with Osteoarthritis: Results from UK Biobank and US NHANES
2023cited by 0position: contributordoi
ALKBH5 promotes PD-L1-mediated immune escape through m6A modification of ZDHHC3 in glioma.
2022cited by 57position: contributordoi
lncRNA XLOC013218 promotes cell proliferation and TMZ resistance by targeting the PIK3R2-mediated PI3K/AKT pathway in glioma.
2022cited by 37position: contributordoi
Comprehensive histological imaging of native microbiota in human glioma.
2022cited by 34position: contributordoi
APOE-ε4 modulates the association among plasma Aβ<sub>42</sub>/Aβ<sub>40</sub>, vascular diseases, neurodegeneration and cognitive decline in non-demented elderly adults.
2022cited by 16position: contributordoi
circRNA-0002109 promotes glioma malignant progression via modulating the miR-129-5P/EMP2 axis.
2022cited by 14position: contributordoi
β-Amyloid discordance of cerebrospinal fluid and positron emission tomography imaging shows distinct spatial tau patterns.
2022cited by 12position: contributordoi
The role of M<sup>6</sup>A modification in the regulation of tumor-related lncRNAs.
2021cited by 65position: contributordoi
Exosome-mediated transfer of MIF confers temozolomide resistance by regulating TIMP3/PI3K/AKT axis in gliomas.
2021cited by 35position: contributordoi
SNAP25 Inhibits Glioma Progression by Regulating Synapse Plasticity <i>via</i> GLS-Mediated Glutaminolysis.
2021cited by 30position: contributordoi
Pentraxin 3 secreted by human adipose-derived stem cells promotes dopaminergic neuron repair in Parkinson's disease via the inhibition of apoptosis.
2021cited by 16position: contributordoi
Comprehensive histological imaging of native microbiota in human glioma
2021cited by 0position: contributordoi

Grants

No grants ingested yet.

Frequent collaborators

· 16 papers (2020–2026)Kevin W. Williams · Southwestern Medical Center4 papers (2016–2019)Jia Sun · Southwestern Medical Center4 papers (2016–2019)Yiru Huang · Fudan University4 papers (2016–2018)Rui-tao Wang · Harbin Medical University3 papers (2016–2017)Zhenyan He · Southwestern Medical Center3 papers (2016–2019)Xingxing Kong · Fudan University3 papers (2016–2017)Andrew Emili · Oregon Health & Science University3 papers (2014–2020)Yongsheng Chang · Shihezi University3 papers (2016–2017)Kai jiang Yu · Harbin Medical University3 papers (2016–2017)Hong Chen · Fujian University of Traditional Chinese Medicine3 papers (2016–2017)Ting Yao · Fudan University3 papers (2016–2017)Yong Gao · The University of Texas Southwestern Medical Center3 papers (2016–2017)Jianqun Yan · Xi'an Jiaotong University3 papers (2016–2017)Zhuo Deng · The University of Texas Southwestern Medical Center2 papers (2016–2017)Jonathan B. Olsen · Bristol-Myers Squibb (Germany)2 papers (2014–2014)Xin Zhang · Capital Institute of Pediatrics1 papers (2018–2018)Wu Wei · Shandong Agricultural University1 papers (2025–2025)Haitao Sun · Jilin University1 papers (2025–2025)Boyang Liu · Zhujiang Hospital1 papers (2022–2022)