Area of research
Neurology · Cell Biology
Research interest
Research focused on LRRK2 and Cell biology, with related work in Oxidative stress, Parkinson's disease, Dopamine. Notable publications include 'GTPase activity regulates kinase activity and cellular phenotypes of Parkinson's disease-associated LRRK2', 'Recent findings on the physiological function of DJ-1: Beyond Parkinson's disease', and 'The G2019S variant of leucine-rich repeat kinase 2 (LRRK2) alters endolysosomal trafficking by impairing the function of the GTPase RAB8A'.
LRRK2 G2019S kinase activity triggers neurotoxic NSF aggregation
Divergent Effects of G2019S and R1441C LRRK2 Mutations on LRRK2 and Rab10 Phosphorylations in Mouse Tissues
The G2019S variant of leucine-rich repeat kinase 2 (LRRK2) alters endolysosomal trafficking by impairing the function of the GTPase RAB8A
Transcriptome analysis of LRRK2 knock-out microglia cells reveals alterations of inflammatory- and oxidative stress-related pathways upon treatment with α-synuclein fibrils
LRRK2 G2019S kinase activity triggers neurotoxic NSF aggregation
Diabetes Mellitus as a Risk Factor for Parkinson’s Disease: a Molecular Point of View
Dopamine Oxidation Products as Mitochondrial Endotoxins, a Potential Molecular Mechanism for Preferential Neurodegeneration in Parkinson’s Disease
The LRRK2 Variant E193K Prevents Mitochondrial Fission Upon MPP+ Treatment by Altering LRRK2 Binding to DRP1
Superoxide dismutating molecules rescue the toxic effects of PINK1 and parkin loss
Recent findings on the physiological function of DJ-1: Beyond Parkinson's disease
Role of LRRK2 in the regulation of dopamine receptor trafficking
GTPase activity regulates kinase activity and cellular phenotypes of Parkinson's disease-associated LRRK2