Area of research
Molecular Biology · Genetics
Research interest
Research interests include Congenital heart defects research, Genomics and Chromatin Dynamics, CRISPR and Genetic Engineering, and RNA Research and Splicing.
Functional dissection of human cardiac enhancers and noncoding de novo variants in congenital heart disease
Dynamic changes in P300 enhancers and enhancer-promoter contacts control mouse cardiomyocyte maturation
Ryanodine receptor 2 (RYR2) dysfunction activates the unfolded protein response and perturbs cardiomyocyte maturation
Enhancer dependence of cell-type–specific gene expression increases with developmental age
A reference map of murine cardiac transcription factor chromatin occupancy identifies dynamic and conserved enhancers
Hierarchical and stage-specific regulation of murine cardiomyocyte maturation by serum response factor
VEGF amplifies transcription through ETS1 acetylation to enable angiogenesis
Mapping cell type-specific transcriptional enhancers using high affinity, lineage-specific Ep300 bioChIP-seq
EED orchestration of heart maturation through interaction with HDACs is H3K27me3-independent
Acetylation of VGLL4 Regulates Hippo-YAP Signaling and Postnatal Cardiac Growth
Cardiac-Specific YAP Activation Improves Cardiac Function and Survival in an Experimental Murine MI Model
<i>Pi3kcb</i> Links Hippo-YAP and PI3K-AKT Signaling Pathways to Promote Cardiomyocyte Proliferation and Survival
Interrogating translational efficiency and lineage-specific transcriptomes using ribosome affinity purification