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Christine Guthrie

University of California, San Francisco · US
Area of research
Molecular Biology
Research interest
Research interests include RNA Research and Splicing, RNA and protein synthesis mechanisms, RNA modifications and cancer, and Genomics and Chromatin Dynamics.
h-index
67
citations
16,664
works
156
NIH funding
primary concept
email

Recent publications

Evolutionarily Conserved Polyadenosine RNA Binding Protein Nab2 Cooperates with Splicing Machinery To Regulate the Fate of Pre-mRNA
Molecular and Cellular Biology 2016cited by 82position: middledoi
SR protein kinases promote splicing of nonconsensus introns
Nature Structural & Molecular Biology 2015cited by 44position: lastdoi
Loss of the Yeast SR Protein Npl3 Alters Gene Expression Due to Transcription Readthrough
PLoS Genetics 2015cited by 38position: middledoi
From Structure to Systems: High-Resolution, Quantitative Genetic Analysis of RNA Polymerase II
Cell 2013cited by 161position: middledoi
Colony PCR
Methods in enzymology on CD-ROM/Methods in enzymology 2013cited by 95position: lastdoi
Biased Brownian ratcheting leads to pre-mRNA remodeling and capture prior to first-step splicing
Nature Structural & Molecular Biology 2013cited by 68position: middledoi
Hierarchical Modularity and the Evolution of Genetic Interactomes across Species
Molecular Cell 2012cited by 247position: middledoi
The Yeast SR-Like Protein Npl3 Links Chromatin Modification to mRNA Processing
PLoS Genetics 2012cited by 61position: lastdoi

Grants

Genetic Analysis of Small Nuclear RNA Structure and Function in Yeast
NSF8905258$70,0001989–1990PIRePORTER
Genetic Analysis of Small Nuclear RNA Structure and Functionin Yeast
NSF8603926$377,1781986–1989PIRePORTER
Genetic Analysis of Small Nuclear Rna Structure and FunctionIn Yeast
NSF8303667$354,4451983–1986PIRePORTER
Specificity and Regulation of Trna Processing Enzymes
NSF7912081$127,0841979–1983PIRePORTER
In Vitro Synthesis of Trna: Regulation of Gene Expression By Rna Processing
NSF7621474$50,0001977–1979PIRePORTER

Frequent collaborators

Nevan J. Krogan · QB32 papers (2012–2013)Megan Bergkessel · University of Dundee2 papers (2013–2016)Erica A. Moehle · Howard Hughes Medical Institute2 papers (2012–2013)John Abelson · University of California, San Francisco1 papers (2013–2013)Alex Tuck · University of Edinburgh1 papers (2015–2015)Lars M. Steinmetz · European Molecular Biology Laboratory1 papers (2015–2015)Yujia A. Chan · Massachusetts Institute of Technology1 papers (2013–2013)Sharon Soucek · Emory University1 papers (2016–2016) · 1 papers (2012–2012)Nils G. Walter · University of Michigan–Ann Arbor1 papers (2013–2013)David Tollervey · University of Edinburgh1 papers (2015–2015)Nicholas T. Seyfried · Emory Healthcare1 papers (2016–2016)Jesse Lipp · Research Institute of Molecular Pathology1 papers (2015–2015)Craig D. Kaplan · Texas A&M University1 papers (2013–2013)Colm J. Ryan · University College Dublin1 papers (2012–2012)Frank C. P. Holstege · Princess Máxima Center1 papers (2013–2013)Anita H. Corbett · Florida State University1 papers (2016–2016) · 1 papers (2013–2013)Mario R. Blanco · California Institute of Technology1 papers (2013–2013)James S. Fraser · University of California, San Francisco1 papers (2013–2013)