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Adrian R. Krainer

Tsinghua University · CN
Area of research
Molecular Biology · Genetics
Research interest
Research focused on RNA splicing and Cell biology, with related work in Oligonucleotide, CTCF, RNA-binding protein. Notable publications include 'The human splicing code reveals new insights into the genetic determinants of disease', 'RNA therapeutics: beyond RNA interference and antisense oligonucleotides', and 'CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function'.
h-index
citations
5,396
works
11
NIH funding
primary concept
email

Recent publications

Evidence generation and reproducibility in cell and gene therapy research: A call to action
Molecular Therapy — Methods & Clinical Development 2021cited by 22position: middledoi
Targeting an RNA-Binding Protein Network in Acute Myeloid Leukemia
Cancer Cell 2019cited by 369position: middledoi
Antisense Oligonucleotide Therapies for Neurodegenerative Diseases
Annual Review of Neuroscience 2019cited by 340position: middledoi
CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function
Cell 2015cited by 1,046position: middledoi
The human splicing code reveals new insights into the genetic determinants of disease
Science 2014cited by 1,298position: middledoi
HITS-CLIP and Integrative Modeling Define the Rbfox Splicing-Regulatory Network Linked to Brain Development and Autism
Cell Reports 2014cited by 367position: middledoi
DAZL Limits Pluripotency, Differentiation, and Apoptosis in Developing Primordial Germ Cells
Stem Cell Reports 2014cited by 105position: middledoi
p53Ψ is a transcriptionally inactive p53 isoform able to reprogram cells toward a metastatic-like state
Proceedings of the National Academy of Sciences 2014cited by 94position: middledoi
OLego: fast and sensitive mapping of spliced mRNA-Seq reads using small seeds
Nucleic Acids Research 2013cited by 139position: middledoi
RNA therapeutics: beyond RNA interference and antisense oligonucleotides
Nature Reviews Drug Discovery 2012cited by 1,149position: middledoi
The splicing factor SRSF1 regulates apoptosis and proliferation to promote mammary epithelial cell transformation
Nature Structural & Molecular Biology 2012cited by 467position: lastdoi

Grants

No grants ingested yet.

Frequent collaborators

Michael Qi Zhang · The University of Texas at Dallas2 papers (2013–2015)Olga Anczuków · Université Claude Bernard Lyon 12 papers (2012–2013)Jie Wu · Anhui Medical University2 papers (2013–2014)Chaolin Zhang · Columbia University Irving Medical Center2 papers (2013–2014)Senthil K. Muthuswamy · Center for Cancer Research1 papers (2012–2012)Akiko Yabuuchi · Harvard Stem Cell Institute1 papers (2014–2014)Alessandro Pastore · Novartis (United States)1 papers (2019–2019)Kuan‐Ting Lin · National Taiwan University1 papers (2019–2019)Brendan J. Frey · University of Toronto1 papers (2014–2014)Sidney Altman · Yale University1 papers (2012–2012)Trushar Rathod · Eunice Kennedy Shriver National Institute of Child Health and Human Development1 papers (2014–2014) · 1 papers (2014–2014)Serge Gueroussov · Tango Therapeutics (United States)1 papers (2014–2014)Zhan Yao · Loxo Oncology at Lilly (United States)1 papers (2014–2014)Margaret Herre · Cornell University1 papers (2014–2014) · 1 papers (2014–2014) · 1 papers (2019–2019)Qinghong Yan · Columbia University1 papers (2014–2014)Raoul Tibes · New York University1 papers (2019–2019)Kathryn Hockemeyer · New York University1 papers (2019–2019)