Area of research
Computational Theory and Mathematics · Molecular Biology
Research interest
Research focused on Cell biology and COPI, with related work in Bruton's tyrosine kinase, Sorting nexin, RAR-related orphan receptor gamma. Notable publications include 'COPI–TRAPPII activates Rab18 and regulates its lipid droplet association', 'Discovery of thalidomide-based PROTAC small molecules as the highly efficient SHP2 degraders', and 'Structural Feature Analyzation Strategies toward Discovery of Orally Bioavailable PROTACs of Bruton’s Tyrosine Kinase for the Treatment of Lymphoma'.
Inhibiting sorting nexin 10 promotes mucosal healing through SREBP2-mediated stemness restoration of intestinal stem cells
Predicting the retention time of Synthetic Cannabinoids using a combinatorial QSAR approach
Structural Feature Analyzation Strategies toward Discovery of Orally Bioavailable PROTACs of Bruton’s Tyrosine Kinase for the Treatment of Lymphoma
Discovery of thalidomide-based PROTAC small molecules as the highly efficient SHP2 degraders
Discovery of betulinaldehyde as a natural RORγt agonist
COPI–TRAPPII activates Rab18 and regulates its lipid droplet association