Area of research
Immunology · Oncology
Research interest
Research interests include CAR-T cell therapy research, Monoclonal and Polyclonal Antibodies Research, Immunotherapy and Immune Responses, and Immune Cell Function and Interaction.
HITM-SURE: Hepatic immunotherapy for metastases phase Ib anti-CEA CAR-T study utilizing pressure enabled drug delivery
Antigen Specificity Enhances Disease Control by Tregs in Vitiligo
HITM-SIR: phase Ib trial of intraarterial chimeric antigen receptor T-cell therapy and selective internal radiation therapy for CEA+ liver metastases
STAT3 inhibition induces Bax-dependent apoptosis in liver tumor myeloid-derived suppressor cells
Engineering Axl specific CAR and SynNotch receptor for cancer therapy
Frontline Science: Functionally impaired geriatric CAR-T cells rescued by increased α5β1 integrin expression
Phase I Trial of Anti‐PSMA Designer CAR‐T Cells in Prostate Cancer: Possible Role for Interacting Interleukin 2‐T Cell Pharmacodynamics as a Determinant of Clinical Response
Regional CAR-T cell infusions for peritoneal carcinomatosis are superior to systemic delivery
Tumor-associated GM-CSF overexpression induces immunoinhibitory molecules via STAT3 in myeloid-suppressor cells infiltrating liver metastases
Liver myeloid-derived suppressor cells expand in response to liver metastases in mice and inhibit the anti-tumor efficacy of anti-CEA CAR-T
T cell exhaustion and Interleukin 2 downregulation
T-Cell Immunotherapy: Looking Forward
Neutrophil:lymphocyte ratios and serum cytokine changes after hepatic artery chimeric antigen receptor-modified T-cell infusions for liver metastases
Biliary obstruction results in PD-1-dependent liver T cell dysfunction and acute inflammation mediated by Th17 cells and neutrophils
Suppression of Human Glioma Xenografts with Second-Generation IL13R-Specific Chimeric Antigen Receptor–Modified T Cells