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Célio X.C. Santos

British Heart Foundation ·
Area of research
Physiology · Immunology
Research interest
Research interests include Nitric Oxide and Endothelin Effects, Neutrophil, Myeloperoxidase and Oxidative Mechanisms, Redox biology and oxidative stress, and Endoplasmic Reticulum Stress and Disease.
h-index
38
citations
7,143
works
74
NIH funding
primary concept
Chemistry
email

Recent publications

NRF2 activation in the heart induces glucose metabolic reprogramming and reduces cardiac dysfunction via upregulation of the pentose phosphate pathway
Cardiovascular Research 2024cited by 26position: middledoi
Human blood vessel organoids reveal a critical role for CTGF in maintaining microvascular integrity
Nature Communications 2023cited by 34position: middledoi
The regulation of cardiac intermediary metabolism by NADPH oxidases
Cardiovascular Research 2022cited by 39position: middledoi
Pkm2 Regulates Cardiomyocyte Cell Cycle and Promotes Cardiac Regeneration
Circulation 2020cited by 278position: middledoi
Nox4 regulates InsP <sub>3</sub> receptor‐dependent Ca <sup>2+</sup> release into mitochondria to promote cell survival
The EMBO Journal 2020cited by 85position: middledoi
Fibroblast Nox2 (NADPH Oxidase-2) Regulates ANG II (Angiotensin II)–Induced Vascular Remodeling and Hypertension via Paracrine Signaling to Vascular Smooth Muscle Cells
Arteriosclerosis Thrombosis and Vascular Biology 2020cited by 47position: middledoi
Blood Pressure–Lowering by the Antioxidant Resveratrol Is Counterintuitively Mediated by Oxidation of cGMP-Dependent Protein Kinase
Circulation 2019cited by 79position: middledoi
Klotho regulation by albuminuria is dependent on ATF3 and endoplasmic reticulum stress
The FASEB Journal 2019cited by 32position: middledoi
Reactive oxygen species regulate axonal regeneration through the release of exosomal NADPH oxidase 2 complexes into injured axons
Nature Cell Biology 2018cited by 328position: middledoi
Publisher Correction: Reactive oxygen species regulate axonal regeneration through the release of exosomal NADPH oxidase 2 complexes into injured axons
Nature Cell Biology 2018cited by 25position: middledoi
Distinct Regulatory Effects of Myeloid Cell and Endothelial Cell NAPDH Oxidase 2 on Blood Pressure
Circulation 2017cited by 61position: middledoi
Nox4 reprograms cardiac substrate metabolism via protein O-GlcNAcylation to enhance stress adaptation
JCI Insight 2017cited by 57position: middledoi
Hypoxia induces heart regeneration in adult mice
Nature 2016cited by 693position: middledoi
Targeted redox inhibition of protein phosphatase 1 by Nox4 regulates <scp>eIF</scp> 2α‐mediated stress signaling
The EMBO Journal 2016cited by 116position: firstdoi
Redox signaling in the cardiomyocyte: From physiology to failure
The International Journal of Biochemistry & Cell Biology 2016cited by 53position: firstdoi
Cell-specific effects of Nox2 on the acute and chronic response to myocardial infarction
Journal of Molecular and Cellular Cardiology 2016cited by 50position: middledoi
Contractile Function During Angiotensin-II Activation
Journal of the American College of Cardiology 2015cited by 94position: middledoi
Transcriptional Regulation of Cystathionine-γ-Lyase in Endothelial Cells by NADPH Oxidase 4-Dependent Signaling
Journal of Biological Chemistry 2015cited by 53position: middledoi
The Oxygen-Rich Postnatal Environment Induces Cardiomyocyte Cell-Cycle Arrest through DNA Damage Response
Cell 2014cited by 886position: middledoi
Redox regulation of cardiac hypertrophy
Journal of Molecular and Cellular Cardiology 2014cited by 126position: middledoi
Endoplasmic Reticulum Stress and Nox-Mediated Reactive Oxygen Species Signaling in the Peripheral Vasculature: Potential Role in Hypertension
Antioxidants and Redox Signaling 2013cited by 138position: firstdoi
Pathological Cardiac Hypertrophy Alters Intracellular Targeting of Phosphodiesterase Type 5 From Nitric Oxide Synthase-3 to Natriuretic Peptide Signaling
Circulation 2012cited by 47position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Ajay M. Shah · Abasyn University22 papers (2012–2024)Alison C. Brewer · British Heart Foundation7 papers (2015–2020)Min Zhang · Wuhan Children's Hospital6 papers (2015–2024)Anna Zoccarato · King's College London4 papers (2017–2024)Manuel Mayr · Imperial College London4 papers (2017–2023)Greta J. Sawyer · King's College London4 papers (2016–2024)Philip Eaton · Queen Mary University of London4 papers (2012–2019)Anne D. Hafstad · British Heart Foundation4 papers (2016–2024)Katrin Schröder · Federal Ministry of Justice and Consumer Protection3 papers (2016–2020)Adam Nabeebaccus · British Heart Foundation3 papers (2013–2022)Matteo Beretta · University of Turin3 papers (2016–2020)Xiaoke Yin · British Heart Foundation3 papers (2017–2023)Daniel A. Richards · King's College London3 papers (2017–2024)Christina M. Reumiller · British Heart Foundation3 papers (2022–2024)Roland A. Fleck · King's College London3 papers (2018–2020)Oleksandra Prysyazhna · Queen Mary University of London3 papers (2015–2019)Daniel B. Martin · Fred Hutch Cancer Center3 papers (2015–2016)Thomas Carroll · Case Western Reserve University2 papers (2018–2018)Francesco De Virgiliis · University of Tübingen2 papers (2018–2018)Guiping Kong · University of Tübingen2 papers (2018–2018)