Area of research
Inorganic Chemistry · Biomedical Engineering
Research interest
Research topics from publications: Transition-metal-functionalized ordered mesoporous silicas: an overview of sustainable chiral catalysts for enantioselective transformations; A dynamic kinetic asymmetric transfer hydrogenation–cyclization tandem reaction: an easy access to chiral 3,4-dihydro-2H-pyran-carbonitriles. Representative work: This review focuses on the development of ordered mesoporous silica-supported chiral transition-metal-based catalysts for enantioselective transformations A chiral (mesitylene)RuCl(monosulfonated diamine) catalysed dynamic kinetic resolution (DKR)-asymmetric transfer hydrogenation (ATH) process is developed for highly enantio- (up to 99% ee) and diastereo- (up to 98 : 2 dr) selective reduction of challenging racemic α-aryl-γ-keto malononitriles. A spontaneous cyclization reaction of the hydrogenation products delivers a cascade process for efficient synthesis of useful enantioenriched 3,4-dihydro-2H-pyran-carbonitriles