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Bernard Klein

University Hospital Heidelberg · DE
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Area of research
Hematology · Immunology
Research interest
Research focused on Multiple myeloma and Carcinoembryonic antigen, with related work in Monoclonal gammopathy of undetermined significance, Cancer research, Cell adhesion molecule. Notable publications include 'Comprehensive characterization of the mutational landscape in multiple myeloma cell lines reveals potential drivers and pathways associated with tumor progression and drug...', 'Tumor cells in multiple myeloma patients inhibit myeloma-reactive T cells through carcinoembryonic antigen-related cell adhesion molecule-6', and 'Preclinical efficacy of sepantronium bromide (YM155) in multiple myeloma is conferred by down regulation of Mcl-1'.
h-index
citations
200
works
11
NIH funding
primary concept
email

Recent publications

Optimisation of anti-interleukin-6 therapy: Precision medicine through mathematical modelling
Frontiers in Immunology 2022cited by 19position: lastdoi
Comprehensive characterization of the mutational landscape in multiple myeloma cell lines reveals potential drivers and pathways associated with tumor progression and drug resistance
Theranostics 2019cited by 85position: middledoi
Asymptomatic Multiple Myeloma – Molecular Background of Progression and Prognosis
Clinical Lymphoma Myeloma & Leukemia 2017cited by 0position: middledoi
Asymptomatic Multiple Myeloma - Background of Progression, Evolution, and Prognosis
Blood 2016cited by 4position: middledoi
Preclinical efficacy of sepantronium bromide (YM155) in multiple myeloma is conferred by down regulation of Mcl-1
Oncotarget 2014cited by 23position: middledoi
Tumor cells in multiple myeloma patients inhibit myeloma-reactive T cells through carcinoembryonic antigen-related cell adhesion molecule-6
Blood 2013cited by 46position: middledoi
The Glycome of Normal and Malignant Plasma Cells
PLoS ONE 2013cited by 17position: middledoi
Expression Quantitative Trait Loci Reveal Regulatory Regions Important In The Pathogenesis of Multiple Myeloma
Blood 2013cited by 0position: middledoi
Thalidomide maintenance therapy maturates the T cell compartment and compromises antigen-specific antitumor immunity in patients with multiple myeloma
Experimental Hematology 2012cited by 6position: middledoi
1101 Human Tumor Cells Inhibit T Cell Responses Through Expression of Carcinoembryonic-antigen-related Cell Adhesion Molecule-6 (CEACAM-6)
European Journal of Cancer 2012cited by 0position: middledoi
Human Multiple Myeloma and Breast Cancer Cells Evade Immune Rejection Through Expression of Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6.
Blood 2012cited by 0position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Dirk Hose · Biotronik (Switzerland)9 papers (2012–2017)Anja Seckinger · Vrije Universiteit Brussel7 papers (2012–2017)Hartmut Goldschmidt · Virginia Cooperative Extension6 papers (2012–2014)Anthony D. Ho · Mayo Clinic in Arizona6 papers (2012–2017)Tobias Meißner · Yale Cancer Center5 papers (2012–2014)Mathias Witzens‐Harig · Deutsche Gesellschaft für Hämatologie und Medizinische Onkologie4 papers (2012–2013)Philipp Beckhove · University Hospital Regensburg4 papers (2012–2013)Thierry Rème · University Hospital Heidelberg4 papers (2012–2017)Anna Jauch · Heidelberg University3 papers (2013–2017)Jérôme Moreaux · University Hospital Heidelberg3 papers (2013–2019)Nisit Khandelwal · Max Planck Institute of Neurobiology3 papers (2012–2013) · 3 papers (2012–2022)Kai Neben · Klinikum Mittelbaden3 papers (2012–2013)Christina Pfirschke · Center for Systems Biology3 papers (2012–2013)Heinke Conrad · University of North Carolina at Chapel Hill3 papers (2012–2013)Michael Hundemer · Virginia Cooperative Extension3 papers (2012–2013)Thomas Hielscher · German Cancer Research Center3 papers (2013–2017)Marcel Mohr · University Hospital Heidelberg2 papers (2016–2017)Bettina Brackertz · MorphoSys (Germany)2 papers (2012–2013)Paul Theodor Pyl · Lund University2 papers (2016–2017)
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