Area of research
Oncology · Molecular Biology
Research interest
Research interests include Cancer-related Molecular Pathways, Epigenetics and DNA Methylation, Cancer Genomics and Diagnostics, and Carcinogens and Genotoxicity Assessment.
Modeling cancer driver events in vitro using barrier bypass-clonal expansion assays and massively parallel sequencing
Modelling mutational landscapes of human cancers in vitro
Comparison of the metabolic activation of environmental carcinogens in mouse embryonic stem cells and mouse embryonic fibroblasts
A Novel p53 Mutant Found in Iatrogenic Urothelial Cancers Is Dysfunctional and Can Be Rescued by a Second-site Global Suppressor Mutation
Mammalian cells acquire epigenetic hallmarks of human cancer during immortalization
Efficient introduction of specific TP53 mutations into mouse embryonic fibroblasts and embryonic stem cells
Humanised Mouse Models: Targeting the Murine p53 Locus with Human Sequences