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Mark L. Paddock

University of California San Diego · US
Area of research
Molecular Biology · Renewable Energy, Sustainability and the Environment
Research interest
Research interests include Photosynthetic Processes and Mechanisms, Metalloenzymes and iron-sulfur proteins, Spectroscopy and Quantum Chemical Studies, and Metal-Catalyzed Oxygenation Mechanisms.
h-index
30
citations
3,006
works
80
NIH funding
primary concept
email

Recent publications

A Combined Computational and Genetic Approach Uncovers Network Interactions of the Cyanobacterial Circadian Clock
Journal of Bacteriology 2016cited by 48position: middledoi
Cancer-Related NEET Proteins Transfer 2Fe-2S Clusters to Anamorsin, a Protein Required for Cytosolic Iron-Sulfur Cluster Biogenesis
PLoS ONE 2015cited by 89position: middledoi
The Fe-S cluster-containing NEET proteins mitoNEET and NAF-1 as chemotherapeutic targets in breast cancer
Proceedings of the National Academy of Sciences 2015cited by 81position: middledoi
Activation of apoptosis in NAF-1-deficient human epithelial breast cancer cells
Journal of Cell Science 2015cited by 60position: middledoi
Structure–function analysis of NEET proteins uncovers their role as key regulators of iron and ROS homeostasis in health and disease
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2014cited by 203position: middledoi
Integrated strategy reveals the protein interface between cancer targets Bcl-2 and NAF-1
Proceedings of the National Academy of Sciences 2014cited by 62position: middledoi
A point mutation in the [2Fe–2S] cluster binding region of the NAF-1 protein (H114C) dramatically hinders the cluster donor properties
Acta Crystallographica Section D Biological Crystallography 2014cited by 42position: middledoi
NAF-1 and mitoNEET are central to human breast cancer proliferation by maintaining mitochondrial homeostasis and promoting tumor growth
Proceedings of the National Academy of Sciences 2013cited by 221position: middledoi
Nutrient-Deprivation Autophagy Factor-1 (NAF-1): Biochemical Properties of a Novel Cellular Target for Anti-Diabetic Drugs
PLoS ONE 2013cited by 47position: middledoi
Characterization of <i>Arabidopsis</i> NEET Reveals an Ancient Role for NEET Proteins in Iron Metabolism
The Plant Cell 2012cited by 107position: middledoi
NADPH Inhibits [2Fe-2S] Cluster Protein Transfer from Diabetes Drug Target MitoNEET to an Apo-acceptor Protein
Journal of Biological Chemistry 2012cited by 40position: middledoi
Allosteric control in a metalloprotein dramatically alters function
Proceedings of the National Academy of Sciences 2012cited by 26position: middledoi

Grants

Operational Support For the Douglas Lake Biological Station
NSF7614961$63,2001977–1979PIRePORTER
Analytical Animal Ecology
NSF7301070$61,0001973–1976PIRePORTER

Frequent collaborators

Patricia A. Jennings · University of San Diego11 papers (2012–2015)Rachel Nechushtai · Hebrew University of Jerusalem11 papers (2012–2015)Ron Mittler · Hebrew University of Jerusalem9 papers (2012–2015)Sagi Tamir · Hebrew University of Jerusalem7 papers (2013–2015)José N. Onuchic · Center for Theoretical Biological Physics7 papers (2012–2015)Colin H. Lipper · Harvard University6 papers (2013–2015)Andrea R. Conlan · University of California San Diego5 papers (2012–2014)John A. Zuris · Editas Medicine (United States)5 papers (2012–2014)Dorit Michaeli · Hebrew University of Jerusalem5 papers (2012–2015)Yang‐Sung Sohn · Hebrew University of Jerusalem4 papers (2013–2015)Faruck Morcos · The University of Texas at Dallas4 papers (2014–2016)Sarah H. Holt · Virginia Tech4 papers (2013–2015)Luhua Song · University of North Texas4 papers (2012–2015)Yael Harir · Hebrew University of Jerusalem3 papers (2012–2013)Yuting Luo · Sun Yat-sen University3 papers (2012–2015)Z. Ioav Cabantchik · Hebrew University of Jerusalem2 papers (2012–2013)Jason T. Stofleth · Ajinomoto (United States)2 papers (2014–2014)Y. Eisenberg-Domovich · Hebrew University of Jerusalem2 papers (2012–2014)Merav Darash Yahana · Hebrew University of Jerusalem2 papers (2015–2015)Oded Livnah · Hebrew University of Jerusalem2 papers (2012–2014)