Area of research
Genetics · Surgery
Research interest
Research focused on Genetics and Imputation (statistics), with related work in Haplotype, Assortative mating, Genome-wide association study. Notable publications include 'The UK10K project identifies rare variants in health and disease', 'Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel', and 'Genetic evidence of assortative mating in humans'.
Genetic evidence of assortative mating in humans
Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis
Mendelian Randomisation study of the influence of eGFR on coronary heart disease
The UK10K project identifies rare variants in health and disease
Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel
TCTEX1D2 mutations underlie Jeune asphyxiating thoracic dystrophy with impaired retrograde intraflagellar transport
Lipids, obesity and gallbladder disease in women: insights from genetic studies using the cardiovascular gene-centric 50K SNP array
A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans
Canonical Correlation Analysis for Gene-Based Pleiotropy Discovery
Apolipoprotein E genotype, cardiovascular biomarkers and risk of stroke: Systematic review and meta-analysis of 14 015 stroke cases and pooled analysis of primary biomarker data from up to 60 883 individuals
Secretory Phospholipase A2-IIA and Cardiovascular Disease
Correction: Population Genomics of Cardiometabolic Traits: Design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium
Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci
Influence of common genetic variation on blood lipid levels, cardiovascular risk, and coronary events in two British prospective cohort studies
A gene-centric analysis of activated partial thromboplastin time and activated protein C resistance using the HumanCVD focused genotyping array
Integration of Genetics into a Systems Model of Electrocardiographic Traits Using HumanCVD BeadChip