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Xavier Soler

Regeneron (United States) · US
Area of research
Pulmonary and Respiratory Medicine · Physiology
Research interest
Research interests include Asthma and respiratory diseases, Chronic Obstructive Pulmonary Disease (COPD) Research, IL-33, ST2, and ILC Pathways, and Respiratory and Cough-Related Research.
h-index
37
citations
4,553
works
176
NIH funding
primary concept
email

Recent publications

Effect of dupilumab on exhaled nitric oxide, mucus plugs, and functional respiratory imaging in patients with type 2 asthma (VESTIGE): a randomised, double-blind, placebo-controlled, phase 4 trial
The Lancet Respiratory Medicine 2025cited by 63position: middledoi
Current Smoker: A Clinical Chronic Obstructive Pulmonary Disease Phenotype Affecting Disease Progression and Response to Therapy
American Journal of Respiratory and Critical Care Medicine 2025cited by 21position: middledoi
Effect of dupilumab on mucus burden in patients with moderate-to-severe asthma: the VESTIGE trial
American Journal of Respiratory and Critical Care Medicine 2025cited by 9position: middledoi
Le dupilumab réduit l’obstruction et le volume du mucus : essai de phase 4 VESTIGE
Revue des Maladies Respiratoires Actualités 2025cited by 0position: middledoi
AERIFY-1/2: two phase 3, randomised, controlled trials of itepekimab in former smokers with moderate-to-severe COPD
ERJ Open Research 2024cited by 29position: middledoi
Biomarkers Associated with Lung Function Decline and Dupilumab Response in Patients with Asthma
American Journal of Respiratory and Critical Care Medicine 2024cited by 26position: middledoi
Chronic Obstructive Pulmonary Disease Exacerbations Increase the Risk of Subsequent Cardiovascular Events: A Longitudinal Analysis of the COPDGene Study
Journal of the American Heart Association 2024cited by 19position: middledoi
The Emerging Role of Alarmin-Targeting Biologics in the Treatment of Patients With COPD
CHEST Journal 2024cited by 14position: middledoi
Real-world effectiveness of dupilumab versus benralizumab and mepolizumab
Allergy and Asthma Proceedings 2024cited by 11position: middledoi
The Effect of Chronic Altitude Exposure on Chronic Obstructive Pulmonary Disease Outcomes in the SPIROMICS Cohort: An Observational Cohort Study
American Journal of Respiratory and Critical Care Medicine 2024cited by 10position: middledoi
Evaluating the Effect of Dupilumab on Type 2 Airway Inflammation and Mucus Plugging in Patients with Uncontrolled Moderate-To-Severe Asthma: the VESTIGE Trial
Journal of Allergy and Clinical Immunology 2024cited by 10position: middledoi
Long-Term Dupilumab Efficacy on Severe Exacerbations and Lung Function in Patients with Type 2 Asthma
Annals of the American Thoracic Society 2024cited by 4position: middledoi
Dupilumab reduces mucus plugging and volume: phase 4 VESTIGE trial
2024cited by 3position: middledoi
Effect of Dupilumab Treatment on Mucus Plugging and Mucus Volume in Type 2 Asthma: The Phase 4 VESTIGE Trial
2024cited by 1position: middledoi
Early treatment response to dupilumab on airway inflammation, airway dynamics, and mucus plugging in VESTIGE
2024cited by 1position: middledoi
Évaluation de l’effet du dupilumab sur l’inflammation de type 2 des voies respiratoires et le bouchon de mucus chez les patients souffrant d’asthme modéré à sévère non contrôlé : l’essai VESTIGE
Revue française d'allergologie 2024cited by 0position: middledoi
Dupilumab-treated patients with moderate-to-severe asthma are more likely to meet clinical remission criteria: results from the VESTIGE trial
2024cited by 0position: middledoi
Targeting Type 2 Inflammation and Epithelial Alarmins in Chronic Obstructive Pulmonary Disease: A Biologics Outlook
American Journal of Respiratory and Critical Care Medicine 2023cited by 95position: middledoi
Real-world effectiveness of dupilumab in patients with asthma
Annals of Allergy Asthma & Immunology 2023cited by 18position: middledoi
Prevalence of abnormal spirometry in individuals with a smoking history and no known obstructive lung disease
Respiratory Medicine 2023cited by 15position: middledoi
Dupilumab Efficacy in Patients with Type 2 Asthma with and without Elevated Blood Neutrophils
Journal of Immunology Research 2023cited by 13position: middledoi
Dupilumab Reduces Exacerbations And Improves Lung Function Regardless Of Prior Asthma Exacerbation Status: LIBERTY ASTHMA TRAVERSE Open-Label Extension Study
Journal of Allergy and Clinical Immunology 2023cited by 0position: middledoi
Dupilumab improves exacerbations and lung function irrespective of prior asthma exacerbations: TRAVERSE
Pneumologie 2023cited by 0position: middledoi
S118 Dupilumab efficacy is not affected by prior asthma exacerbation status in LIBERTY ASTHMA TRAVERSE open-label extension study
2023cited by 0position: middledoi
Efficacy of dupilumab in patients with moderate-to-severe asthma and persistent airflow obstruction
Annals of Allergy Asthma & Immunology 2022cited by 14position: middledoi
Pulmonary Arterial Pruning and Longitudinal Change in Percent Emphysema and Lung Function
CHEST Journal 2021cited by 48position: middledoi
Emphysema Progression and Lung Function Decline Among Angiotensin Converting Enzyme Inhibitors and Angiotensin-Receptor Blockade Users in the COPDGene Cohort
CHEST Journal 2021cited by 21position: middledoi
COPDGene® 2019: Redefining the Diagnosis of Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Diseases Journal of the COPD Foundation 2019cited by 180position: middledoi
Causes and Predictors of Death in Smokers with and Without COPD: An Analysis of the COPDGene Cohort
2019cited by 41position: middledoi
Mortality and Exacerbations by Global Initiative for Chronic Obstructive Lung Disease Groups ABCD: 2011 Versus 2017 in the COPDGene® Cohort
Chronic Obstructive Pulmonary Diseases Journal of the COPD Foundation 2019cited by 28position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Juby A. Jacob‐Nara · Novartis (Switzerland)18 papers (2022–2025)Alberto Papi · Instituto de Investigación Sanitaria de Santiago16 papers (2022–2025)Paul J. Rowe · Novartis (Switzerland)14 papers (2022–2025) · 11 papers (2022–2025)Njira Lugogo · Johannes Gutenberg University Mainz10 papers (2023–2025)Mario Castro · University of Kansas Medical Center9 papers (2022–2025)Christopher E. Brightling · University of Leicester9 papers (2024–2025)Celeste Porsbjerg · Azienda Usl Toscana Centro9 papers (2024–2025) · 8 papers (2024–2025) · 8 papers (2024–2025)Arnaud Bourdin · Conseil Régional du Languedoc-Roussillon7 papers (2024–2025) · 5 papers (2023–2025)Edwin K. Silverman · Harvard University5 papers (2013–2019)James D. Crapo · National Jewish Health5 papers (2013–2019)Barry J. Make · Utrecht University5 papers (2013–2019)Fernando J. Martínez · University of Massachusetts Chan Medical School5 papers (2019–2024)Amr Radwan · Novartis (Switzerland)5 papers (2023–2025)Gerard J. Criner · Temple University Hospital4 papers (2016–2025) · 4 papers (2024–2025)Klaus F. Rabe · University of Lübeck4 papers (2023–2025)