Area of research
Immunology · Molecular Biology
Research interest
Research focused on Immunogenicity and Immunology, with related work in Valine, Transplantation, Glutaminolysis. Notable publications include 'Senolytics prevent mt-DNA-induced inflammation and promote the survival of aged organs following transplantation', 'Composite tissue allotransplantation: opportunities and challenges', and 'Targeting age‐specific changes in CD4 + T cell metabolism ameliorates alloimmune responses and prolongs graft survival'.
Idelalisib modulates CD4+ T cell responses to mitigate rejection of allografts in mice
Transplanting old organs promotes senescence in young recipients
Metabolic reprogramming of myeloid-derived suppressor cells in the context of organ transplantation
Targeting age‐specific changes in CD4<sup>+</sup> T cell metabolism ameliorates alloimmune responses and prolongs graft survival
Recipient sex and estradiol levels affect transplant outcomes in an age-specific fashion
Taurodeoxycholic acid and valine reverse obesity-associated augmented alloimmune responses and prolong allograft survival
Restored TDCA and valine levels imitate the effects of bariatric surgery
Senolytics prevent mt-DNA-induced inflammation and promote the survival of aged organs following transplantation
CTLA4-Ig prolongs graft survival specifically in young but not old mice
Composite tissue allotransplantation: opportunities and challenges