Area of research
Molecular Biology · Global and Planetary Change
Research interest
Research interests include Cell death mechanisms and regulation, PI3K/AKT/mTOR signaling in cancer, Climate variability and models, and Plant Water Relations and Carbon Dynamics.
Safety of Early Oral Refeeding in Patients With Chronic Pancreatitis After Extracorporeal Shock Wave Lithotripsy of Pancreatic Stone (SHEEL): A Multicenter Randomized Controlled Trial
Is endoscopic radiofrequency ablation safe and effective for treating rare neuroendocrine tumors of the minor papilla?
Innovative application of a cystotome in the recanalization of a tight pancreatic duct stricture for abscess drainage.
Proton pump inhibitors may enhance the risk of digestive diseases by regulating intestinal microbiota
The gut microbiome dysbiosis and regulation by fecal microbiota transplantation: umbrella review
Safety of high-carbohydrate fluid diet 2 h versus overnight fasting before non-emergency endoscopic retrograde cholangiopancreatography: A single-blind, multicenter, randomized controlled trial
Taking a high-carbohydrate liquid diet two hours before ERCP in non-emergency patients was as safe as overnight fasting: A single-blind, multicentre, randomised controlled trial
A novel machine learning model and a public online prediction platform for prediction of post-ERCP-cholecystitis (PEC)
Chinese expert recommendations on management of hepatocellular carcinoma during COVID-19 pandemic: a nationwide multicenter survey
Optimal dilation time for combined small endoscopic sphincterotomy and balloon dilation for common bile duct stones: a multicentre, single-blinded, randomised controlled trial
Met gene amplification and protein hyperactivation is a mechanism of resistance to both first and third generation EGFR inhibitors in lung cancer treatment
Expression of Death Receptor 4 Is Positively Regulated by MEK/ERK/AP-1 Signaling and Suppressed upon MEK Inhibition
mTOR Complex 2 Stabilizes Mcl-1 Protein by Suppressing Its Glycogen Synthase Kinase 3-Dependent and SCF-FBXW7-Mediated Degradation
Enhancing therapeutic efficacy of the MEK inhibitor, MEK162, by blocking autophagy or inhibiting PI3K/Akt signaling in human lung cancer cells
Suppression of death receptor 5 enhances cancer cell invasion and metastasis through activation of caspase-8/TRAF2-mediated signaling
The novel proteasome inhibitor carfilzomib activates and enhances extrinsic apoptosis involving stabilization of death receptor 5
The BET bromodomain inhibitor, JQ1, facilitates c-FLIP degradation and enhances TRAIL-induced apoptosis independent of BRD4 and c-Myc inhibition
Poly (<scp>ADP</scp>) ribose polymerase enzyme inhibitor, veliparib, potentiates chemotherapy and radiation in vitro and in vivo in small cell lung cancer
Maintaining Glycogen Synthase Kinase-3 Activity Is Critical for mTOR Kinase Inhibitors to Inhibit Cancer Cell Growth
The E3 ubiquitin ligases β-TrCP and FBXW7 cooperatively mediates GSK3-dependent Mcl-1 degradation induced by the Akt inhibitor API-1, resulting in apoptosis
Protein Phosphatase 2A and DNA-dependent Protein Kinase Are Involved in Mediating Rapamycin-induced Akt Phosphorylation
mTOR Complex 2 Is Involved in Regulation of Cbl-Dependent c-FLIP Degradation and Sensitivity of TRAIL-Induced Apoptosis
Elevated expression of eukaryotic translation initiation factor 4E is associated with proliferation, invasion and acquired resistance to erlotinib in lung cancer
The combination of RAD001 and NVP-BKM120 synergistically inhibits the growth of lung cancer in vitro and in vivo