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Zhizhong Pan

Sun Yat-sen University · CN
Area of research
Oncology · Pathology and Forensic Medicine
Research interest
Research interests include Colorectal Cancer Surgical Treatments, Colorectal Cancer Treatments and Studies, Genetic factors in colorectal cancer, and Colorectal and Anal Carcinomas.
h-index
40
citations
6,501
works
345
NIH funding
primary concept
Medicine
email

Recent publications

Cancer associated fibroblasts-derived lactate induces oxaliplatin treatment resistance by promoting cancer stemness via ANTXR1 lactylation in colorectal cancer
Cancer Letters 2025cited by 17position: middledoi
Colonoscopy outcomes of primary screening negative participants highlight the missed diagnosis problem of colorectal cancer screening: an observational study from Yuexiu district in Guangzhou, China
Frontiers in Oncology 2025cited by 0position: middledoi
Effect of neoadjuvant chemoradiotherapy with or without PD-1 antibody sintilimab in pMMR locally advanced rectal cancer: A randomized clinical trial
Cancer Cell 2024cited by 78position: middledoi
Spatially organized tumor-stroma boundary determines the efficacy of immunotherapy in colorectal cancer patients
Nature Communications 2024cited by 63position: middledoi
Long-Term Outcomes of dMMR/MSI-H Rectal Cancer Treated With Anti–PD-1–Based Immunotherapy as Curative-Intent Treatment
Journal of the National Comprehensive Cancer Network 2024cited by 23position: middledoi
Laparoscopy-assisted versus open surgery for low rectal cancer (LASRE): 3-year survival outcomes of a multicentre, randomised, controlled, non-inferiority trial
˜The œLancet. Gastroenterology & hepatology 2024cited by 22position: middledoi
Cetuximab plus FOLFOXIRI versus cetuximab plus FOLFOX as conversion regimen in RAS/BRAF wild-type patients with initially unresectable colorectal liver metastases (TRICE trial): A randomized controlled trial
PLoS Medicine 2024cited by 17position: middledoi
A 5-Hydroxymethylcytosine-Based Noninvasive Model for Early Detection of Colorectal Carcinomas and Advanced Adenomas: The METHOD-2 Study
Clinical Cancer Research 2024cited by 10position: middledoi
609O CLDN18.2 targeted antibody-drug conjugate (ADC), SHR-A1904, in patients (pts) with gastric/gastroesophageal junction cancer (GC/GEJC): A phase I study
Annals of Oncology 2024cited by 9position: middledoi
Tumor-derived lactate promotes resistance to bevacizumab treatment by facilitating autophagy enhancer protein RUBCNL expression through histone H3 lysine 18 lactylation (H3K18la) in colorectal cancer
Autophagy 2023cited by 373position: middledoi
Neoadjuvant PD-1 blockade with sintilimab in mismatch-repair deficient, locally advanced rectal cancer: an open-label, single-centre phase 2 study
˜The œLancet. Gastroenterology & hepatology 2023cited by 134position: middledoi
A positive feedback circuit driven by m6A-modified circular RNA facilitates colorectal cancer liver metastasis
Molecular Cancer 2023cited by 52position: middledoi
Neoadjuvant Immunotherapy Leads to Major Response and Low Recurrence in Localized Mismatch Repair–Deficient Colorectal Cancer
Journal of the National Comprehensive Cancer Network 2023cited by 40position: middledoi
Lymphovascular invasion represents a superior prognostic and predictive pathological factor of the duration of adjuvant chemotherapy for stage III colon cancer patients
BMC Cancer 2023cited by 20position: middledoi
CACA guidelines for holistic integrative management of rectal cancer
Holistic Integrative Oncology 2023cited by 5position: middledoi
Inflammation promotes resistance to immune checkpoint inhibitors in high microsatellite instability colorectal cancer
Nature Communications 2022cited by 147position: middledoi
Short-term Outcomes of Laparoscopy-Assisted vs Open Surgery for Patients With Low Rectal Cancer
JAMA Oncology 2022cited by 94position: middledoi
Comprehensive profiling of 1015 patients’ exomes reveals genomic-clinical associations in colorectal cancer
Nature Communications 2022cited by 82position: middledoi
Neoadjuvant Chemotherapy With CAPOX Versus Chemoradiation for Locally Advanced Rectal Cancer With Uninvolved Mesorectal Fascia (CONVERT): Initial Results of a Phase III Trial
Annals of Surgery 2022cited by 80position: middledoi
Clinical actionability of triaging DNA mismatch repair deficient colorectal cancer from biopsy samples using deep learning
EBioMedicine 2022cited by 42position: middledoi
Anti-PD-1-based immunotherapy as curative-intent treatment in dMMR/MSI-H rectal cancer: A multicentre cohort study
European Journal of Cancer 2022cited by 39position: middledoi
Postoperative circulating tumor DNA as markers of recurrence risk in stages II to III colorectal cancer
Journal of Hematology & Oncology 2021cited by 182position: middledoi
CMTM6 and PD-L1 coexpression is associated with an active immune microenvironment and a favorable prognosis in colorectal cancer
Journal for ImmunoTherapy of Cancer 2021cited by 79position: middledoi
Dynamic monitoring of circulating tumor DNA to predict prognosis and efficacy of adjuvant chemotherapy after resection of colorectal liver metastases
Theranostics 2021cited by 76position: middledoi
TRIM25 regulates oxaliplatin resistance in colorectal cancer by promoting EZH2 stability
Cell Death and Disease 2021cited by 64position: middledoi
Dickkopf 1 impairs the tumor response to PD-1 blockade by inactivating CD8+ T cells in deficient mismatch repair colorectal cancer
Journal for ImmunoTherapy of Cancer 2021cited by 59position: middledoi
N6-methyladenosine modification of circNSUN2 facilitates cytoplasmic export and stabilizes HMGA2 to promote colorectal liver metastasis
Nature Communications 2019cited by 836position: middledoi
Stress–glucocorticoid–TSC22D3 axis compromises therapy-induced antitumor immunity
Nature Medicine 2019cited by 362position: middledoi
Expert consensus on multidisciplinary therapy of colorectal cancer with lung metastases (2019 edition)
Journal of Hematology & Oncology 2019cited by 121position: middledoi
PIWI-interacting RNA-54265 is oncogenic and a potential therapeutic target in colorectal adenocarcinoma
Theranostics 2018cited by 165position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Peirong Ding · Wuhan Union Hospital8 papers (2021–2025)Jianhong Peng · Kunming University of Science and Technology6 papers (2018–2025)Zhenhai Lu · State Key Laboratory of Oncology in South China6 papers (2018–2025)Jiang Wu · Xihua University6 papers (2021–2024)Ling-Heng Kong · Sun Yat-sen University6 papers (2021–2024)Qingjian Ou · Tongji University5 papers (2021–2025)Ranyi Liu · Sun Yat-sen University5 papers (2013–2021)Kai Han · China Agricultural University5 papers (2019–2024)Junzhong Lin · Sun Yat-sen University5 papers (2023–2025)Binyi Xiao · Sun Yat-sen University5 papers (2021–2024)Jinghua Tang · Sun Yat-sen University5 papers (2021–2024)Wenlin Huang · Longyan University5 papers (2013–2021)Rui‐Hua Xu · Henan Medical University5 papers (2019–2024)Wei-Jian Mei · Sun Yat-sen University4 papers (2022–2024)Leen Liao · Sun Yat-sen University4 papers (2021–2025)Weihao Li · Sun Yat-sen University4 papers (2022–2025)Yujing Fang · Foshan University4 papers (2021–2025)Jiangxue Wu · Sun Yat-sen University4 papers (2013–2017)Chi Zhou · University of Arizona3 papers (2022–2023)Rongxin Zhang · Ministry of Education of the People's Republic of China3 papers (2018–2023)