Area of research
Surgery · Cancer Research
Research interest
Research interests include Pancreatitis Pathology and Treatment, MicroRNA in disease regulation, Nanoplatforms for cancer theranostics, and Protein Degradation and Inhibitors.
Discovery of degrader for FLT3, GSPT1 and IKZF1/3 proteins merging PROTAC and molecular glue targeting FLT3-ITD mutant acute myeloid leukemia
Design, synthesis, and evaluation of 1,3,4-oxadiazole-based EGFR inhibitors
Selective degradation of hyperphosphorylated tau by proteolysis-targeting chimeras ameliorates cognitive function in Alzheimer’s disease model mice
An overview of PROTACs: a promising drug discovery paradigm
Discovery of the first potent proteolysis targeting chimera (PROTAC) degrader of indoleamine 2,3-dioxygenase 1
Discovery and biological evaluation of darolutamide derivatives as inhibitors and down-regulators of wild-type AR and the mutants