Area of research
Molecular Biology · Cellular and Molecular Neuroscience
Research interest
Research focused on Receptor and G protein-coupled receptor, with related work in Glucagon receptor, Transmembrane domain, Glucagon-like peptide-1. Notable publications include 'Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors', 'Structural basis for the tethered peptide activation of adhesion GPCRs', and 'Structural basis for activation of the growth hormone-releasing hormone receptor'.
Structural pharmacology and mechanisms of GLP-1R signaling
Molecular features of the ligand-free GLP-1R, GCGR and GIPR in complex with Gs proteins
Structural insights into the triple agonism at GLP-1R, GIPR and GCGR manifested by retatrutide
Structural analysis of the dual agonism at GLP-1R and GCGR
Structural insights into ligand recognition and subtype selectivity of the human melanocortin-3 and melanocortin-5 receptors
Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors
Structural basis for the tethered peptide activation of adhesion GPCRs
Structural perspective of class B1 GPCR signaling
Structural insights into hormone recognition by the human glucose-dependent insulinotropic polypeptide receptor
Structural basis for activation of the growth hormone-releasing hormone receptor
A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor