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Sophie Léon

Université Claude Bernard Lyon 1 · FR
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Area of research
Oncology · Pulmonary and Respiratory Medicine
Research interest
Research focused on Cancer research and Downregulation and upregulation, with related work in Tumor microenvironment, Carboplatin, Netrin. Notable publications include 'Regulatory T cells promote cancer immune-escape through integrin αvβ8-mediated TGF-β activation', 'Netrin-1 blockade inhibits tumour growth and EMT features in endometrial cancer', and 'Epithelial-to-mesenchymal transition promotes immune escape by inducing CD70 in non-small cell lung cancer'.
h-index
citations
436
works
7
NIH funding
primary concept
email

Recent publications

Netrin-1 blockade inhibits tumour growth and EMT features in endometrial cancer
Nature 2023cited by 142position: middledoi
Fusion-negative rhabdomyosarcoma 3D organoids to predict effective drug combinations: A proof-of-concept on cell death inducers
Cell Reports Medicine 2023cited by 16position: middledoi
Epithelial-to-mesenchymal transition promotes immune escape by inducing CD70 in non-small cell lung cancer
European Journal of Cancer 2022cited by 32position: middledoi
Regulatory T cells promote cancer immune-escape through integrin αvβ8-mediated TGF-β activation
Nature Communications 2021cited by 161position: middledoi
Lipoic acid decreases breast cancer cell proliferation by inhibiting IGF-1R via furin downregulation
British Journal of Cancer 2020cited by 31position: middledoi
The Ectodysplasin receptor EDAR acts as a tumor suppressor in melanoma by conditionally inducing cell death
Cell Death and Differentiation 2018cited by 31position: middledoi
Targeting netrin‐1/DCC interaction in diffuse large B‐cell and mantle cell lymphomas
EMBO Molecular Medicine 2016cited by 23position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Marie Castets · Université Claude Bernard Lyon 12 papers (2016–2018)Julien C. Marie · Université Claude Bernard Lyon 12 papers (2016–2021)Patrick Mehlen · Université Claude Bernard Lyon 12 papers (2016–2018)Marion Creveaux · Université Claude Bernard Lyon 12 papers (2016–2018)Nicolas Gadot · Université Claude Bernard Lyon 12 papers (2016–2020)Antonin Tortereau · Université Claude Bernard Lyon 12 papers (2016–2018)Stéphane Dalle · Université Claude Bernard Lyon 12 papers (2018–2021)Jonathan Vial · Université Claude Bernard Lyon 12 papers (2016–2018)Sébastien This · Université Claude Bernard Lyon 11 papers (2021–2021)Alexandra Traverse‐Glehen · Université Claude Bernard Lyon 11 papers (2016–2016)Sarah Dinvaut · Université Claude Bernard Lyon 11 papers (2018–2018)Laura Broutier · Centre Léon Bérard1 papers (2016–2016)Dean Sheppard · Pulmonary and Critical Care Associates1 papers (2021–2021)Sophie Pantalacci · Université Claude Bernard Lyon 11 papers (2018–2018)Diana Farhat · Université Claude Bernard Lyon 11 papers (2020–2020) · 1 papers (2016–2016)Karin Tarte · Université Bretagne Loire1 papers (2016–2016)Denis Maillet · Université de Lorraine1 papers (2018–2018)Catherine Chassagne‐Clément · Université Claude Bernard Lyon 11 papers (2016–2016)Muriel Le Romancer · Université Claude Bernard Lyon 11 papers (2020–2020)
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