Area of research
Molecular Biology · Genetics
Research interest
Research focused on Cancer research and PD-L1, with related work in Glycosylation, Breast cancer, Immune system. Notable publications include 'Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity', 'PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis', and 'STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion'.
Targeting ALK averts ribonuclease 1-induced immunosuppression and enhances antitumor immunity in hepatocellular carcinoma
Inhibition of Galectin-9 sensitizes tumors to anthracycline treatment via inducing antitumor immunity
Erratum to ‘Ribonuclease 7-driven activation of ROS1 is a potential therapeutic target in hepatocellular carcinoma’ [J Hepatol 2021 (907-918)]
Human ribonuclease 1 serves as a secretory ligand of ephrin A4 receptor and induces breast tumor initiation
PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis
Ribonuclease 7-driven activation of ROS1 is a potential therapeutic target in hepatocellular carcinoma
Removal of N-Linked Glycosylation Enhances PD-L1 Detection and Predicts Anti-PD-1/PD-L1 Therapeutic Efficacy
IL-6/JAK1 pathway drives PD-L1 Y112 phosphorylation to promote cancer immune evasion
MET Inhibitors Promote Liver Tumor Evasion of the Immune Response by Stabilizing PDL1
CDK2-mediated site-specific phosphorylation of EZH2 drives and maintains triple-negative breast cancer
STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion
Targeting PKCδ as a Therapeutic Strategy against Heterogeneous Mechanisms of EGFR Inhibitor Resistance in EGFR-Mutant Lung Cancer
JAK2-binding long noncoding RNA promotes breast cancer brain metastasis
Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity
Expression of metastasis suppressor BRMS1 in breast cancer cells results in a marked delay in cellular adhesion to matrix