Area of research
Genetics · Pulmonary and Respiratory Medicine
Research interest
Research interests include Glioma Diagnosis and Treatment, Prostate Cancer Treatment and Research, Meningioma and schwannoma management, and Cancer-related molecular mechanisms research.
Spatial genomic, biochemical and cellular mechanisms underlying meningioma heterogeneity and evolution
In vivo perturb-seq of cancer and microenvironment cells dissects oncologic drivers and radiotherapy responses in glioblastoma
Glioblastoma remodelling of human neural circuits decreases survival
Granulin loss of function in human mature brain organoids implicates astrocytes in TDP-43 pathology
Multiomic screening of invasive GBM cells reveals targetable transsulfuration pathway alterations
Meningioma DNA methylation groups identify biological drivers and therapeutic vulnerabilities
CRISPRi-based radiation modifier screen identifies long non-coding RNA therapeutic targets in glioma
Multiplatform genomic profiling and magnetic resonance imaging identify mechanisms underlying intratumor heterogeneity in meningioma
TAMI-21. MALIGNANT GLIOMAS REMODEL FUNCTIONAL NEURAL CIRCUITS THROUGH PARACRINE SIGNALING WHICH CONFERS A NEGATIVE PROGNOSIS
Systematic Three-Dimensional Coculture Rapidly Recapitulates Interactions between Human Neurons and Astrocytes