Area of research
Oncology · Surgery · mRNA vaccine · mRNA Vaccines
Research interest
Research interests include Pancreatic and Hepatic Oncology Research, Organ Transplantation Techniques and Outcomes, Hepatocellular Carcinoma Treatment and Prognosis, and Cancer Immunotherapy and Biomarkers.
Preoperative prediction of early recurrence in pancreatic cancer: A novel clinical-radiomics model.
Erythrocyte-anti-PD1 conjugates in persons with advanced solid tumors resistant to anti-PD1/PDL1: preclinical characterization and results of a phase 1 trial.
Publisher Correction: Shear stress governs hematopoietic stem cell fate to promote inflammation-induced aging.
Shear stress governs hematopoietic stem cell fate to promote inflammation-induced aging.
Tumor-associated CD19<sup>+</sup> macrophages induce immunosuppressive microenvironment in hepatocellular carcinoma.
Pancreatic-targeted lipid nanoparticles based on organ capsule filtration.
Genetic engineering of systemically injectable oncolytic viruses for pyroptosis-accelerated cancer virotherapy.
Oncolytic virus VG161 in refractory hepatocellular carcinoma
Oncolytic virus VG161 in refractory hepatocellular carcinoma.
Sphingolipid synthesis in tumor-associated macrophages confers immunotherapy resistance in hepatocellular carcinoma.
First-in-class PD-1/IL-2 bispecific antibody IBI363 in patients (Pts) with advanced immunotherapy-treated non-small cell lung cancer (NSCLC).
Harnessing amino acid pathways to influence myeloid cell function in tumor immunity
Lipid metabolism reprograming by SREBP1-PCSK9 targeting sensitizes pancreatic cancer to immunochemotherapy.
Targeting spermine metabolism to overcome immunotherapy resistance in pancreatic cancer.
A novel FAP-targeting antibody-exatecan conjugate improves immune checkpoint blockade by reversing immunosuppressive microenvironment in pancreatic cancer.
Ubiquitination by HRD1 is essential for TLR3 trafficking and its innate immune signaling.
Publisher Correction: Oncolytic virus VG161 in refractory hepatocellular carcinoma.
Specific pathogen free ten gene-edited donor pigs for xenotransplantation.
In-depth plasma proteomics reveals the dynamic changes and prognostic biomarkers for chimeric antigen receptor-glypican-3 T-cell therapy in patients with hepatocellular carcinoma.
IRE1α translational suppression potentiates STING-dependent chemoresistance in pancreatic cancer.
Utilization of Whole Slide Pathological Images and Tumor Clinical Data: A Hybrid Graph Convolutional Network Model for Hepatocellular Carcinoma Prognosis Prediction
Innate immune sensing of lysosomal dysfunction drives multiple lysosomal storage disorders.
IRF3 activates RB to authorize cGAS-STING-induced senescence and mitigate liver fibrosis.
Targeting cancer-associated fibroblast autophagy renders pancreatic cancer eradicable with immunochemotherapy by inhibiting adaptive immune resistance.
Fructose-1,6-bisphosphatase 1 dephosphorylates and inhibits TERT for tumor suppression.
Envafolimab plus lenvatinib and transcatheter arterial chemoembolization for unresectable hepatocellular carcinoma: a prospective, single-arm, phase II study.
Nuclear KRT19 is a transcriptional corepressor promoting histone deacetylation and liver tumorigenesis
TFPI from erythroblasts drives heme production in central macrophages promoting erythropoiesis in polycythemia
TFPI from erythroblasts drives heme production in central macrophages promoting erythropoiesis in polycythemia.
Clinical characteristics and outcomes of liver transplant recipients infected by Omicron during the opening up of the dynamic zero-coronavirus disease policy in China: A prospective, observational study