Area of research
Molecular Biology
Research interest
Research interests include CRISPR and Genetic Engineering, RNA and protein synthesis mechanisms, Fungal and yeast genetics research, and Gene Regulatory Network Analysis.
The convergence of AI-driven engineering biology and emerging technologies advancing globally networked autonomous biofoundries
TargetMITO: A rule-based model for generating highly functional synthetic mitochondrial targeting sequence in yeast
The design and engineering of synthetic genomes.
Construction and iterative redesign of synXVI a 903 kb synthetic Saccharomyces cerevisiae chromosome.
Synthetic yeast genome SCRaMbLEing uncovers a new role for ribosomal proteins in genetic code expansion
Synthetic yeast genome SCRaMbLEing uncovers a new role for ribosomal proteins in genetic code expansion
A new set of mutations in the second transmembrane helix of the Cox2p-W56R substantially improves its allotopic expression in Saccharomyces cerevisiae.
Confronting risks of mirror life.
Large-scale genomic rearrangements boost SCRaMbLE in Saccharomyces cerevisiae.
Engineering stringent genetic biocontainment of yeast with a protein stability switch.
High plasticity of ribosomal DNA organization in budding yeast
Searching for the optimal microbial factory: high-throughput biosensors and analytical techniques for screening small molecules.
Methodological advances enabled by the construction of a synthetic yeast genome.
Challenges to rhizobial adaptability in a changing climate: Genetic engineering solutions for stress tolerance.
Heterologous pulcherrimin production in Saccharomyces cerevisiae confers inhibitory activity on Botrytis conidiation.
The de novo design and synthesis of yeast chromosome XIII facilitates investigations on aging.
An efficient pyrrolysyl-tRNA synthetase for economical production of MeHis-containing enzymes.
Yeasty HAC Does the Trick
Debugging and consolidating multiple synthetic chromosomes reveals combinatorial genetic interactions
Design, construction, and functional characterization of a tRNA neochromosome in yeast.
Safety by design: Biosafety and biosecurity in the age of synthetic genomics.
Dissecting aneuploidy phenotypes by constructing Sc2.0 chromosome VII and SCRaMbLEing synthetic disomic yeast.
Synthetic yeast chromosome XI design provides a testbed for the study of extrachromosomal circular DNA dynamics.
Establishing chromosomal design-build-test-learn through a synthetic chromosome and its combinatorial reconfiguration
Building a eukaryotic chromosome arm by de novo design and synthesis.
Parallel laboratory evolution and rational debugging reveal genomic plasticity to <i>S. cerevisiae</i> synthetic chromosome XIV defects.
A spotlight on global collaboration in the Sc2.0 yeast consortium.
Cellular Surveillance: DNA-Based Recording to Monitor and Memorize Biological Events
Large-scale genomic rearrangements boost SCRaMbLE in
<i>Saccharomyces cerevisiae</i>
Engineering stringent genetic biocontainment of yeast with a protein stability switch