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Matthias W. Hentze

European Bioinformatics Institute · GB
Area of research
Molecular Biology · Hematology
Research interest
Research interests include RNA Research and Splicing, RNA and protein synthesis mechanisms, RNA modifications and cancer, and Iron Metabolism and Disorders.
h-index
119
citations
53,143
works
405
NIH funding
primary concept
email

Recent publications

Genomic G quadruplexes regulate mRNA splicing
bioRxiv (Cold Spring Harbor Laboratory) 2025cited by 1position: middledoi
Superparamagnetic Iron Oxide Nanoparticles Reprogram the Tumor Microenvironment and Reduce Lung Cancer Regrowth after Crizotinib Treatment
ACS Nano 2024cited by 35position: middledoi
Inflammation-driven NF-κB signaling represses ferroportin transcription in macrophages via HDAC1 and HDAC3
Blood 2024cited by 25position: middledoi
Systematic analysis of RNA-binding proteins identifies targetable therapeutic vulnerabilities in osteosarcoma
Nature Communications 2024cited by 10position: middledoi
The RNA-binding protein landscapes differ between mammalian organs and cultured cells
Nature Communications 2023cited by 44position: lastdoi
The RNA-binding protein landscapes differ between mammalian organs and cultured cells
bioRxiv (Cold Spring Harbor Laboratory) 2022cited by 5position: lastdoi
NMD inhibition by 5-azacytidine augments presentation of immunogenic frameshift-derived neoepitopes
iScience 2021cited by 49position: middledoi
Core Cross‐Linked Polymeric Micelles for Specific Iron Delivery: Inducing Sterile Inflammation in Macrophages
Advanced Healthcare Materials 2021cited by 34position: middledoi
Constitutional PIGA mutations cause a novel subtype of hemochromatosis in patients with neurologic dysfunction
Blood 2021cited by 18position: middledoi
Condensation of Ded1p Promotes a Translational Switch from Housekeeping to Stress Protein Production
Cell 2020cited by 244position: middledoi
Pharmacological inhibition of nonsense-mediated RNA decay augments HLA class I-mediated presentation of neoepitopes in MSI CRC
bioRxiv (Cold Spring Harbor Laboratory) 2020cited by 2position: middledoi
The RNA-Binding Protein YBX3 Controls Amino Acid Levels by Regulating SLC mRNA Abundance
Cell Reports 2019cited by 101position: lastdoi
S1631 UNEXPECTED DIFFERENCES IN CARDIAC IRON METABOLISM AND SURVIVAL IN HAMP‐KO AND FPN(C326S) MICE
HemaSphere 2019cited by 0position: middledoi
A brave new world of RNA-binding proteins
Nature Reviews Molecular Cell Biology 2018cited by 1,874position: firstdoi
The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest
Cell 2018cited by 448position: middledoi
The Human RNA-Binding Proteome and Its Dynamics During Arsenite-Induced Translational Arrest
bioRxiv (Cold Spring Harbor Laboratory) 2018cited by 7position: middledoi
A Red Carpet for Iron Metabolism
Cell 2017cited by 1,304position: middledoi
Iron Induces Anti-tumor Activity in Tumor-Associated Macrophages
Frontiers in Immunology 2017cited by 165position: middledoi
Insights into the design and interpretation of iCLIP experiments
Genome biology 2017cited by 99position: middledoi
Specific RNP capture with antisense LNA/DNA mixmers
RNA 2017cited by 72position: lastdoi
Identification of RNA-binding domains of RNA-binding proteins in cultured cells on a system-wide scale with RBDmap
Nature Protocols 2017cited by 48position: lastdoi
The actin-binding protein profilin 2 is a novel regulator of iron homeostasis
Blood 2017cited by 35position: middledoi
Comprehensive Identification of RNA-Binding Domains in Human Cells
Molecular Cell 2016cited by 672position: lastdoi
Iron-regulatory proteins secure iron availability in cardiomyocytes to prevent heart failure
European Heart Journal 2016cited by 183position: middledoi
Global changes of the RNA-bound proteome during the maternal-to-zygotic transition in Drosophila
Nature Communications 2016cited by 169position: middledoi
Iron accelerates cardiovascular disease: The importance of maintaining iron balance
Atherosclerosis 2016cited by 2position: middledoi
A novel inflammatory pathway mediating rapid hepcidin-independent hypoferremia
Blood 2015cited by 171position: middledoi
Ferritin-Mediated Iron Sequestration Stabilizes Hypoxia-Inducible Factor-1α upon LPS Activation in the Presence of Ample Oxygen
Cell Reports 2015cited by 109position: middledoi
Comprehensive Identification of RNA-Binding Proteins by RNA Interactome Capture
Methods in molecular biology 2015cited by 68position: lastdoi
Eisenüberladung in adulten Hfe-defizienten Mäusen unabhängig von Veränderungen in der Expression der duodenalen Eisentransporter DMT1 und Ireg1/Ferroportin
Zeitschrift für Gastroenterologie 2015cited by 0position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Martina U. Muckenthaler · University Medical Centre Mannheim13 papers (2013–2024)Bruno Galy · German Cancer Research Center12 papers (2013–2023)Jeroen Krijgsveld · Medical Research Council8 papers (2015–2019)Sandro Altamura · Heidelberg University7 papers (2013–2024)Thomas Schwarzl · European Bioinformatics Institute6 papers (2018–2023)Alfredo Castelló · University of Oxford6 papers (2015–2018)Mandy Rettel · European Molecular Biology Laboratory6 papers (2017–2024)Andreas E. Kulozik · German Cancer Research Center5 papers (2017–2024)Frank Stein · European Bioinformatics Institute5 papers (2020–2024)Bernd Fischer · Stellenbosch University5 papers (2015–2017)Oriana Marques · European Molecular Biology Organization4 papers (2021–2024)Rastislav Horos · European Molecular Biology Laboratory4 papers (2015–2018)Ina Huppertz · University of California, Santa Cruz4 papers (2017–2023)Silvia Colucci · University Hospital Heidelberg3 papers (2021–2024)Anne-Marie Alleaume · European Bioinformatics Institute3 papers (2016–2019)H. J. Gröne · German Cancer Research Center3 papers (2013–2019)Natalie K. Horvat · Emory University3 papers (2021–2024)Dunja Ferring–Appel · European Molecular Biology Laboratory3 papers (2013–2023)Joel I. Perez-Perri · European Molecular Biology Laboratory3 papers (2022–2024)Tomaž Curk · European Molecular Biology Laboratory3 papers (2016–2017)