Area of research
Hematology · Genetics
Research interest
Research interests include Iron Metabolism and Disorders, Hemoglobinopathies and Related Disorders, Trace Elements in Health, and Erythropoietin and Anemia Treatment.
Inflammation-driven NF-κB signaling represses ferroportin transcription in macrophages via HDAC1 and HDAC3
T cell-independent eradication of experimental glioma by intravenous TLR7/8-agonist-loaded nanoparticles
Iron regulatory protein (IRP)–mediated iron homeostasis is critical for neutrophil development and differentiation in the bone marrow
Erythropoietin-driven dynamic proteome adaptations during erythropoiesis prevent iron overload in the developing embryo
IRON REGULATORY PROTEIN (IRP)-MEDIATED IRON HOMEOSTASIS IS CRITICAL FOR NEUTROPHIL DEVELOPMENT AND DIFFERENTIATION IN THE BONE MARROW
3171 – MOUSE MULTIPOTENT PROGENITOR 5 CELLS ARE LOCATED AT THE INTERPHASE BETWEEN HEMATOPOIETIC STEM AND PROGENITOR CELLS
Mouse multipotent progenitor 5 cells are located at the interphase between hematopoietic stem and progenitor cells
Constitutional PIGA mutations cause a novel subtype of hemochromatosis in patients with neurologic dysfunction
Differential Alternative Polyadenylation Landscapes Mediate Hematopoietic Stem Cell Activation and Regulate Glutamine Metabolism
2007 – DIFFERENTIAL ALTERNATIVE POLYADENYLATION LANDSCAPES MEDIATE HEMATOPOIETIC STEM CELL ACTIVATION AND REGULATE GLUTAMINE METABOLISM
Glutathione peroxidase 4 and vitamin E control reticulocyte maturation, stress erythropoiesis and iron homeostasis
Radical sensing keeps noxious iron at bay
ALTERNATIVE POLYADENYLATION REGULATES HEMATOPOIETIC STEM CELL METABOLISM
S1631 UNEXPECTED DIFFERENCES IN CARDIAC IRON METABOLISM AND SURVIVAL IN HAMP‐KO AND FPN(C326S) MICE
Hepcidin-Mediated Ferroportin Control in the Bone Marrow Is Dispensable
Dietary stearic acid regulates mitochondria in vivo in humans
Hematopoietic Stem Cells are Regulated by Alternative Polyadenylation
Vitamin A-Retinoic Acid Signaling Regulates Hematopoietic Stem Cell Dormancy
Disruption of the Hepcidin/Ferroportin Regulatory System Causes Pulmonary Iron Overload and Restrictive Lung Disease
Vitamin A/ retinoic acid signaling regulates hematopoietic stem cell dormancy
Myc Depletion Induces a Pluripotent Dormant State Mimicking Diapause
Transforming Growth Factor β1 (TGF-β1) Activates Hepcidin mRNA Expression in Hepatocytes
Iron accelerates cardiovascular disease: The importance of maintaining iron balance
Transition out of HSC Dormancy By a Continuous Upregulation of Metabolism Is Controlled Via Dietary Vitamin A/ Retinoic Acid Signaling
A novel inflammatory pathway mediating rapid hepcidin-independent hypoferremia
Efficacy and safety of deferasirox in non-thalassemic patients with elevated ferritin levels after allogeneic hematopoietic stem cell transplantation
Resistance of Ferroportin to Hepcidin Binding causes Exocrine Pancreatic Failure and Fatal Iron Overload
In Vivo Disruption Of The Hepcidin−Ferroportin Regulatory Circuitry Causes Fatal Systemic and Exocrine Pancreatic Iron Overload