Area of research
Hematology · Pathology and Forensic Medicine
Research interest
Research interests include Acute Myeloid Leukemia Research, Hematopoietic Stem Cell Transplantation, Lymphoma Diagnosis and Treatment, and Chronic Lymphocytic Leukemia Research.
Continuous map of early hematopoietic stem cell differentiation across human lifetime
Frosted DNA: β‐Galactosidase Control of Oligonucleotide Activity
FACS-Based Assessment of Human Hematopoietic Stem and Progenitor Cells
CRISPR/Cas9 editing of NKG2A improves the efficacy of primary CD33-directed chimeric antigen receptor natural killer cells
Transglutaminase 2 promotes epithelial-to-mesenchymal transition by regulating the expression of matrix metalloproteinase 7 in colorectal cancer cells via the MEK/ERK signaling pathway
Development of a Potent and Selective G2A (GPR132) Agonist
Intracranial injection of natural killer cells engineered with a HER2-targeted chimeric antigen receptor in patients with recurrent glioblastoma
Transglutaminase 2 is associated with adverse colorectal cancer survival and represents a therapeutic target
Wnt/β-Catenin-Signaling Modulates Megakaryopoiesis at the Megakaryocyte-Erythrocyte Progenitor Stage in the Hematopoietic System
The EGR3 regulome of infant KMT2A-r acute lymphoblastic leukemia identifies differential expression of B-lineage genes predictive for outcome
Interaction of inherited genetic variants in the NLRP3 inflammasome/IL-6 pathway with acquired clonal hematopoiesis to modulate mortality risk in patients with HFrEF
Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging
Enhanced but variant-dependent serological and cellular immune responses to third-dose BNT162b2 vaccination in patients with multiple myeloma
CRISPR/Cas9 Gene Editing of Immune Checkpoint Receptor NKG2A Improves the Efficacy of Primary CD33-CAR-NK Cells Against AML
HIV-1 Infection of Long-Lived Hematopoietic Precursors In Vitro and In Vivo
Isolation of murine bone marrow hematopoietic stem and progenitor cell populations via flow cytometry
Time’s up: mutation rate and lifespan
An alternative CYB5A transcript is expressed in aneuploid ALL and enriched in relapse
Severe impairment of T-cell responses to BNT162b2 immunization in patients with multiple myeloma
GPR182 is an endothelium-specific atypical chemokine receptor that maintains hematopoietic stem cell homeostasis
Transglutaminase 2 promotes tumorigenicity of colon cancer cells by inactivation of the tumor suppressor p53
Full Spectrum of Clonal Haematopoiesis-Driver Mutations in Chronic Heart Failure and their Associations with Mortality
Inhibiting casein kinase 2 sensitizes acute lymphoblastic leukemia cells to venetoclax via MCL1 degradation
Carbonic-anhydrase IX expression is increased in thyroid cancer tissue and represents a potential therapeutic target to eradicate thyroid tumor-initiating cells
Editorial commentary: A heartbreaking relationship: Clonal hematopoiesis and heart failure
Clonal Hematopoiesis–Driver DNMT3A Mutations Alter Immune Cells in Heart Failure
Clonal haematopoiesis in chronic ischaemic heart failure: prognostic role of clone size for <i>DNMT3A</i>- and <i>TET2</i>-driver gene mutations
Single-cell RNA-sequencing reveals profound changes in circulating immune cells in patients with heart failure
Differential Alternative Polyadenylation Landscapes Mediate Hematopoietic Stem Cell Activation and Regulate Glutamine Metabolism
Survival differences and associated molecular signatures of DNMT3A-mutant acute myeloid leukemia patients