Area of research
Oncology · Genetics
Research interest
Research interests include CAR-T cell therapy research, Virus-based gene therapy research, Hematopoietic Stem Cell Transplantation, and Immune Cell Function and Interaction.
Enhanced conversion of T cells into CAR T cells by modulation of the MAPK/ERK pathway
Early induction of cytokine release syndrome by rapidly generated CAR T cells in preclinical models
CAR Gene Delivery by T‐cell Targeted Lentiviral Vectors is Enhanced by Rapamycin Induced Reduction of Antiviral Mechanisms
CD62L as target receptor for specific gene delivery into less differentiated human T lymphocytes
Substantially improved gene transfer to interneurons with second-generation glutamate receptor-targeted DART-AAV vectors
In Vivo Generation of CAR T Cells Selectively in Human CD4+ Lymphocytes
Highly Efficient Generation of Transgenically Augmented CAR NK Cells Overexpressing CXCR4
<i>In vivo</i> generated human CAR T cells eradicate tumor cells
Tumor-Specific Delivery of Immune Checkpoint Inhibitors by Engineered AAV Vectors
GluA4-Targeted AAV Vectors Deliver Genes Selectively to Interneurons while Relying on the AAV Receptor for Entry
In vivo generation of human CD19‐CAR T cells results in B‐cell depletion and signs of cytokine release syndrome
Vitamin A-Retinoic Acid Signaling Regulates Hematopoietic Stem Cell Dormancy
Vitamin A/ retinoic acid signaling regulates hematopoietic stem cell dormancy
DNA-damage response gene GADD45A induces differentiation in hematopoietic stem cells without inhibiting cell cycle or survival
Exit from HSC dormancy by a continuous upregulation of metabolism is controlled via vitamin A/ retinoic acid
Transition out of HSC Dormancy By a Continuous Upregulation of Metabolism Is Controlled Via Dietary Vitamin A/ Retinoic Acid Signaling
Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells
STAT5-regulated microRNA-193b controls haematopoietic stem and progenitor cell expansion by modulating cytokine receptor signalling
Single-Stranded DNA-Binding Transcriptional Regulator FUBP1 Is Essential for Fetal and Adult Hematopoietic Stem Cell Self-Renewal
Cytokine-Regulated GADD45G Induces Differentiation and Lineage Selection in Hematopoietic Stem Cells
Altered HSC Metabolism in Response to Stress Leads to De Novo dna Damage and Cellular Attrition
Incomplete cytokinesis and re-fusion of small mononucleated Hodgkin cells lead to giant multinucleated Reed–Sternberg cells