Area of research
Epidemiology · Endocrinology
Research interest
Research interests include Biology, Shigella, Septin, Cell biology, Microbiology, and Shigella flexneri.
Emerging models to study competitive interactions within bacterial communities
ERK activation waves coordinate mechanical cell competition leading to collective elimination via extrusion of bacterially infected cells
Enhanced virulence and stress tolerance are signatures of epidemiologically successful Shigella sonnei
Neutrophils display antibacterial defense via non-canonical LC3 decoration of extracellular bacteria
Why solutions to antimicrobial resistance are urgently needed
Comparative Analysis of Septin Modifiers, Forchlorfenuron and <scp>UR214</scp> ‐9, on Mitochondrial Fragmentation and Lytic Cell Death
Recent advances in modelling Shigella infection
Shigella sonnei: epidemiology, evolution, pathogenesis, resistance and host interactions
Septins promote macrophage pyroptosis by regulating gasdermin D cleavage and ninjurin-1-mediated plasma membrane rupture
Use of zebrafish to identify host responses specific to type VI secretion system mediated interbacterial antagonism
The great escape: a Shigella effector unlocks the septin cage
High-content high-resolution microscopy and deep learning-assisted analysis reveals host and bacterial heterogeneity during Shigella infection
High-content high-resolution microscopy and deep learning assisted analysis reveals host and bacterial heterogeneity during Shigella infection
Rearranging to resist cell death
P1 Bacteriophage-Enabled Delivery of CRISPR-Cas9 Antimicrobial Activity Against <i>Shigella flexneri</i>
<i>Shigella</i> induces epigenetic reprogramming of zebrafish neutrophils
Regulation of integrin α5β1-mediated Staphylococcus aureus cellular invasion by the septin cytoskeleton
<i>Shigella</i> Serotypes Associated With Carriage in Humans Establish Persistent Infection in Zebrafish
An automated microscopy workflow to study <i>Shigella</i> –neutrophil interactions and antibiotic efficacy <i>in vivo</i>
Acquisition of a large virulence plasmid (pINV) promoted temperature-dependent virulence and global dispersal of O96:H19 enteroinvasive <i>Escherichia coli</i>
Zebrafish null mutants of Sept6 and Sept15 are viable but more susceptible to <scp> <i>Shigella</i> </scp> infection
Septins and K63 ubiquitin chains are present in separate bacterial microdomains during autophagy of entrapped <i>Shigella</i>
The septin cytoskeleton: Heteromer composition defines filament function
Transcriptional profiling of zebrafish identifies host factors controlling susceptibility to <i>Shigella flexneri</i>
Interplay between septins and ubiquitin-mediated xenophagy during <i>Shigella</i> entrapment
Pyroptosis in host defence against bacterial infection
Proximity proteomics identifies septins and PAK2 as decisive regulators of actomyosin-mediated expulsion of von Willebrand factor
Septins promote caspase activity and coordinate mitochondrial apoptosis
Louis Pasteur continues to shape the future of microbiology
Mechanistic insight into bacterial entrapment by septin cage reconstitution