Area of research
Endocrinology · Clinical Biochemistry
Research interest
Research focused on Cell biology and Pyroptosis, with related work in Shigella, Septin, Microbiology. Notable publications include 'Pyroptosis in host defence against bacterial infection', 'Shigella induces epigenetic reprogramming of zebrafish neutrophils', and 'Mitochondria: intracellular sentinels of infections'.
ERK activation waves coordinate mechanical cell competition leading to collective elimination via extrusion of bacterially infected cells
Comparative Analysis of Septin Modifiers, Forchlorfenuron and <scp>UR214</scp> ‐9, on Mitochondrial Fragmentation and Lytic Cell Death
Septins promote macrophage pyroptosis by regulating gasdermin D cleavage and ninjurin-1-mediated plasma membrane rupture
High-content high-resolution microscopy and deep learning-assisted analysis reveals host and bacterial heterogeneity during Shigella infection
High-content high-resolution microscopy and deep learning assisted analysis reveals host and bacterial heterogeneity during Shigella infection
Rearranging to resist cell death
<i>Shigella</i> induces epigenetic reprogramming of zebrafish neutrophils
Regulation of integrin α5β1-mediated Staphylococcus aureus cellular invasion by the septin cytoskeleton
<i>Shigella</i> Serotypes Associated With Carriage in Humans Establish Persistent Infection in Zebrafish
Zebrafish null mutants of Sept6 and Sept15 are viable but more susceptible to <scp> <i>Shigella</i> </scp> infection
Hierarchic regulation of a metabolic pathway: H-NS, CRP, and SsrB control <i>myo</i> -inositol utilization by <i>Salmonella enterica</i>
Pyroptosis in host defence against bacterial infection
Mitochondria: intracellular sentinels of infections
Septins promote caspase activity and coordinate mitochondrial apoptosis