Area of research
Molecular Biology · Genetics
Research interest
Research interests include RNA and protein synthesis mechanisms, Bacterial Genetics and Biotechnology, Endoplasmic Reticulum Stress and Disease, and Ubiquitin and proteasome pathways.
Lysosomal GPCR-like protein LYCHOS signals cholesterol sufficiency to mTORC1
Structure of the substrate-engaged SecA-SecY protein translocation machine
Structure of the CLC-1 chloride channel from Homo sapiens
Structural and Mechanistic Insights into Protein Translocation
Crystal structure of a substrate-engaged SecY protein-translocation channel
Structure of a CLC chloride ion channel by cryo-electron microscopy
Structure of the SecY channel during initiation of protein translocation
Mechanisms of Sec61/SecY-Mediated Protein Translocation Across Membranes
Bacterial protein translocation requires only one copy of the SecY complex in vivo