Area of research
Physiology · Psychiatry and Mental health
Research interest
Research interests include Alzheimer's disease research and treatments, Dementia and Cognitive Impairment Research, Parkinson's Disease Mechanisms and Treatments, and Genetic Associations and Epidemiology.
Harmonizing genotype array data to understand genetic risk for brain amyloid burden in the AMYPAD PNHS Consortium
Polygenic pathways shape white matter vulnerability to Alzheimer’s disease-related pathophysiological changes
Plasma pTau181 and pTau217 predict asymptomatic amyloid accumulation equally well as amyloid PET
Age-related changes in tau and autophagy in human brain in the absence of neurodegeneration
Longitudinal associations of serum biomarkers with early cognitive, amyloid and grey matter changes
Longitudinal APOE4- and amyloid-dependent changes in the blood transcriptome in cognitively intact older adults
Longitudinal changes in 18F-Flutemetamol amyloid load in cognitively intact APOE4 carriers versus noncarriers: Methodological considerations
Serum biomarkers for prognosis and monitoring in asymptomatic Alzheimer’s Disease
Differential associations between regional amyloid PET and Alzheimer’s disease polygenic risk scores
Astrocyte calcium dysfunction causes early network hyperactivity in Alzheimer’s disease
Phospho‐specific plasma p‐tau181 assay detects clinical as well as asymptomatic Alzheimer's disease
Classification of 18F-Flutemetamol scans in cognitively normal older adults using machine learning trained with neuropathology as ground truth
Lack of association between bridging integrator 1 ( <i>BIN1</i> ) rs744373 polymorphism and tau‐PET load in cognitively intact older adults
Baseline cognition is the best predictor of 4-year cognitive change in cognitively intact older adults
Comparison of ELISA- and SIMOA-based quantification of plasma Aβ ratios for early detection of cerebral amyloidosis
Comparison of two analytical platforms for blood‐based surrogate biomarkers of amyloid pathology