Area of research
Genetics · Epidemiology
Research interest
Research focused on Inflammatory bowel disease and Inflammatory Bowel Diseases, with related work in Crohn's disease, Primary sclerosing cholangitis, Single-nucleotide polymorphism. Notable publications include 'Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease', 'Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study', and 'Fine-mapping inflammatory bowel disease loci to single-variant resolution'.
Harmonizing genotype array data to understand genetic risk for brain amyloid burden in the AMYPAD PNHS Consortium
Plasma pTau181 and pTau217 predict asymptomatic amyloid accumulation equally well as amyloid PET
Genomic analyses of hair from Ludwig van Beethoven
The genetics of non-monogenic IBD
Longitudinal APOE4- and amyloid-dependent changes in the blood transcriptome in cognitively intact older adults
HLA-DP on Epithelial Cells Enables Tissue Damage by NKp44+ Natural Killer Cells in Ulcerative Colitis
Large-scale sequencing identifies multiple genes and rare variants associated with Crohn’s disease susceptibility
Lack of association between bridging integrator 1 ( <i>BIN1</i> ) rs744373 polymorphism and tau‐PET load in cognitively intact older adults
Association of Plasma p-tau181 and p-tau231 Concentrations With Cognitive Decline in Patients With Probable Dementia With Lewy Bodies
Prostaglandin E <sub>2</sub> receptor PTGER4-expressing macrophages promote intestinal epithelial barrier regeneration upon inflammation
Oncostatin M Is a Biomarker of Diagnosis, Worse Disease Prognosis, and Therapeutic Nonresponse in Inflammatory Bowel Disease
Inflammatory bowel disease and Parkinson’s disease: common pathophysiological links
Genetic contributors to risk of schizophrenia in the presence of a 22q11.2 deletion
Genome-wide association study of Alzheimer’s disease CSF biomarkers in the EMIF-AD Multimodal Biomarker Discovery dataset
An interpretable low-complexity machine learning framework for robust exome-based in-silico diagnosis of Crohn’s disease patients
Intestinal Receptor of SARS-CoV-2 in Inflamed IBD Tissue Seems Downregulated by HNF4A in Ileum and Upregulated by Interferon Regulating Factors in Colon
Extracellular Vesicles in Inflammatory Bowel Disease: Small Particles, Big Players
Genetic Variants of the MGAT5 Gene Are Functionally Implicated in the Modulation of T Cells Glycosylation and Plasma IgG Glycome Composition in Ulcerative Colitis
Quantitative microbiome profiling disentangles inflammation- and bile duct obstruction-associated microbiota alterations across PSC/IBD diagnoses
Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data
Complete Sequence of the 22q11.2 Allele in 1,053 Subjects with 22q11.2 Deletion Syndrome Reveals Modifiers of Conotruncal Heart Defects
Butyrate Does Not Protect Against Inflammation-induced Loss of Epithelial Barrier Function and Cytokine Production in Primary Cell Monolayers From Patients With Ulcerative Colitis
Gene and Mirna Regulatory Networks During Different Stages of Crohn’s Disease
Molecular Profiling of Inflammatory Bowel Disease: Is It Ready for Use in Clinical Decision-Making?
IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes
TREM-1, the ideal predictive biomarker for endoscopic healing in anti-TNF-treated Crohn’s disease patients?
Fine-mapping inflammatory bowel disease loci to single-variant resolution
Genetic and Transcriptomic Bases of Intestinal Epithelial Barrier Dysfunction in Inflammatory Bowel Disease
Genetics of inflammatory bowel disease: beyond NOD2
Risk Stratification for Surgery in Stricturing Ileal Crohn’s Disease: The BACARDI Risk Model