Area of research
Public Health, Environmental and Occupational Health · Infectious Diseases
Research interest
Research interests include Malaria Research and Control, HIV/AIDS drug development and treatment, Mosquito-borne diseases and control, and Drug Transport and Resistance Mechanisms.
The anticancer human mTOR inhibitor sapanisertib potently inhibits multiple <i>Plasmodium</i> kinases and life cycle stages
Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention
The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to <i>Plasmodium falciparum</i> parasite resistance
The antimalarial efficacy and mechanism of resistance of the novel chemotype DDD01034957
Inhibition of Resistance-Refractory P. falciparum Kinase PKG Delivers Prophylactic, Blood Stage, and Transmission-Blocking Antiplasmodial Activity
Combining Stage Specificity and Metabolomic Profiling to Advance Antimalarial Drug Discovery
Covalent Plasmodium falciparum-selective proteasome inhibitors exhibit a low propensity for generating resistance in vitro and synergize with multiple antimalarial agents
Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics
Hexahydroquinolines are antimalarial candidates with potent blood-stage and transmission-blocking activity
Dioxins and related environmental contaminants increase TDP-43 levels