Area of research
Molecular Biology · Spectroscopy
Research interest
Research interests include Ubiquitin, Chemistry, Ubiquitin ligase, Cell biology, Signal transduction, and Biology.
Engineering ERα degraders with pleiotropic ubiquitin ligase ligands maximizes therapeutic efficacy by co-opting distinct effector ligases
An RNA damage response network mediates the lethality of 5-FU in colorectal cancer
Simultaneous substrate and ubiquitin modification recognition by bispecific antibodies enables detection of ubiquitinated RIP1 and RIP2
Systematic pharmacological analysis of agonistic and antagonistic fibroblast growth factor receptor 1 MAbs reveals a similar unique mode of action
Chaperone mediated detection of small molecule target binding in cells
The RIPK4–IRF6 signalling axis safeguards epidermal differentiation and barrier function
Disruption of XIAP-RIP2 Association Blocks NOD2-Mediated Inflammatory Signaling
Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes
USP7 small-molecule inhibitors interfere with ubiquitin binding
Uncovering a Dual Regulatory Role for Caspases During Endoplasmic Reticulum Stress-induced Cell Death
Application of Mass Spectrometry Profiling to Establish Brusatol as an Inhibitor of Global Protein Synthesis
Immunoaffinity Enrichment Coupled to Quantitative Mass Spectrometry Reveals Ubiquitin-Mediated Signaling Events