Area of research
Immunology · Radiology, Nuclear Medicine and Imaging
Research interest
Research interests include Immune Cell Function and Interaction, T-cell and B-cell Immunology, Immunotherapy and Immune Responses, and Monoclonal and Polyclonal Antibodies Research.
Spatial patterning of fibroblast TGFβ signaling underlies treatment resistance in rheumatoid arthritis
Spatial patterning of fibroblast TGFβ signaling underlies treatment resistance in rheumatoid arthritis.
Granzyme K activates the entire complement cascade
Granzyme K activates the entire complement cascade.
Molecular and spatial analysis of tertiary lymphoid structures in Sjogren’s syndrome
Deep immunophenotyping reveals circulating activated lymphocytes in individuals at risk for rheumatoid arthritis
Fibroblasts in immune responses, inflammatory diseases and therapeutic implications.
Blood immunophenotyping identifies distinct kidney histopathology and outcomes in patients with lupus nephritis
A human-mouse atlas of intrarenal myeloid cells identifies conserved disease-associated macrophages in lupus nephritis
Adipose tissue harbors pathogenic T cells in obesity that exacerbate inflammatory arthritis.
Interferon subverts an AHR-JUN axis to promote CXCL13<sup>+</sup> T cells in lupus.
Synovial fibroblast gene expression is associated with sensory nerve growth and pain in rheumatoid arthritis
A longitudinal single-cell atlas of anti-tumour necrosis factor treatment in inflammatory bowel disease.
Tissue-specific enhancer–gene maps from multimodal single-cell data identify causal disease alleles
Clonal associations between lymphocyte subsets and functional states in rheumatoid arthritis synovium
Tissue-specific enhancer-gene maps from multimodal single-cell data identify causal disease alleles.
Clonal associations between lymphocyte subsets and functional states in rheumatoid arthritis synovium.
The chromatin landscape of pathogenic transcriptional cell states in rheumatoid arthritis.
The chromatin landscape of pathogenic transcriptional cell states in rheumatoid arthritis
Adipocyte associated glucocorticoid signaling regulates normal fibroblast function which is lost in inflammatory arthritis
Automated multi-scale computational pathotyping (AMSCP) of inflamed synovial tissue
Publisher Correction: Interferon subverts an AHR-JUN axis to promote CXCL13<sup>+</sup> T cells in lupus.
Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes.
Clonally expanded CD38 <sup>hi</sup> cytotoxic CD8 T cells define the T cell infiltrate in checkpoint inhibitor–associated arthritis
Clonally expanded CD38<sup>hi</sup> cytotoxic CD8 T cells define the T cell infiltrate in checkpoint inhibitor-associated arthritis.
Mapping the dynamic genetic regulatory architecture of HLA genes at single-cell resolution.
Mapping the dynamic genetic regulatory architecture of
<i>HLA</i>
genes at single-cell resolution
Deep immunophenotyping reveals circulating activated lymphocytes in individuals at risk for rheumatoid arthritis
Associations between rheumatoid arthritis clinical factors with synovial cell types and states
Granzyme K <sup>+</sup> CD8 T cells form a core population in inflamed human tissue
CD8 T cell derived Granzyme K activates complement that drives synovial fibroblast inflammation
CD8 T cell derived Granzyme K activates complement that drives synovial fibroblast inflammation
CD8 T cell derived Granzyme K activates complement that drives synovial fibroblast inflammation
Single cell and spatial genomic analyses of specimens from patients with autoimmune diseases (Technology Core)
Single cell and spatial genomic analyses of specimens from patients with autoimmune diseases (Technology Core)
Single cell and spatial genomic analyses of specimens from patients with autoimmune diseases (Technology Core)
Single cell and spatial genomic analyses of specimens from patients with autoimmune diseases (Technology Core)
Single cell and spatial genomic analyses of specimens from patients with autoimmune diseases (Technology Core)
Origin and function of atypical lymphocyte populations in inflamed tissue in SLE and RA
Origin and function of atypical lymphocyte populations in inflamed tissue in SLE and RA
Origin and function of atypical lymphocyte populations in inflamed tissue in SLE and RA
Origin and function of atypical lymphocyte populations in inflamed tissue in SLE and RA
Origin and function of atypical lymphocyte populations in inflamed tissue in SLE and RA
DMREF: Collaborative Research: Digital Magnetic Handshake Materials, Structures, and Machines
Deciphering Pathways Driving Inflammatory Fibroblast Effector Functions in RA
Deciphering Pathways Driving Inflammatory Fibroblast Effector Functions in RA
Deciphering Pathways Driving Inflammatory Fibroblast Effector Functions in RA
Deciphering Pathways Driving Inflammatory Fibroblast Effector Functions in RA
Deciphering Pathways Driving Inflammatory Fibroblast Effector Functions in RA
iNKT cells hyperactivate DCs
iNKT cells hyperactivate DCs
Newly Identified T Peripheral Helper (Tph) Cells in Rheumatoid Arthritis
Newly Identified T Peripheral Helper (Tph) Cells in Rheumatoid Arthritis
Newly Identified T Peripheral Helper (Tph) Cells in Rheumatoid Arthritis
Newly Identified T Peripheral Helper (Tph) Cells in Rheumatoid Arthritis