Area of research
Immunology · Molecular Biology
Research interest
Research interests include Single-cell and spatial transcriptomics, T-cell and B-cell Immunology, Systemic Lupus Erythematosus Research, and Immune Cell Function and Interaction.
Synovial tissue atlas in juvenile idiopathic arthritis reveals pathogenic niches associated with disease severity
Synovial fibroblast gene expression is associated with sensory nerve growth and pain in rheumatoid arthritis
Tissue-specific enhancer–gene maps from multimodal single-cell data identify causal disease alleles
Clonal associations between lymphocyte subsets and functional states in rheumatoid arthritis synovium
The chromatin landscape of pathogenic transcriptional cell states in rheumatoid arthritis
Longitudinal patterns and predictors of response to standard-of-care therapy in lupus nephritis: data from the Accelerating Medicines Partnership Lupus Network
Adipocyte associated glucocorticoid signaling regulates normal fibroblast function which is lost in inflammatory arthritis
Systemic and skin-limited delayed-type drug hypersensitivity reactions associate with distinct resident and recruited T cell subsets
Automated multi-scale computational pathotyping (AMSCP) of inflamed synovial tissue
Mapping the dynamic genetic regulatory architecture of HLA genes at single-cell resolution
Type I interferon signature and cycling lymphocytes in macrophage activation syndrome
Dynamic regulatory elements in single-cell multimodal data implicate key immune cell states enriched for autoimmune disease heritability
Drug Dissolution in Oral Drug Absorption: Workshop Report
Granzyme K <sup>+</sup> CD8 T cells form a core population in inflamed human tissue
Cross-tissue, single-cell stromal atlas identifies shared pathological fibroblast phenotypes in four chronic inflammatory diseases
mTORC1 links pathology in experimental models of Still’s disease and macrophage activation syndrome
High incidence of proliferative and membranous nephritis in SLE patients with low proteinuria in the Accelerating Medicines Partnership
IL-1-driven stromal–neutrophil interactions define a subset of patients with inflammatory bowel disease that does not respond to therapies
Notch signalling drives synovial fibroblast identity and arthritis pathology
Fast, sensitive and accurate integration of single-cell data with Harmony
Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry
Distinct fibroblast subsets drive inflammation and damage in arthritis
HBEGF <sup>+</sup> macrophages in rheumatoid arthritis induce fibroblast invasiveness
Metabolic reprogramming of natural killer cells in obesity limits antitumor responses
Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis
Methods for high-dimensional analysis of cells dissociated from cryopreserved synovial tissue
Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis
Capture and Stimulated Release of Circulating Tumor Cells on Polymer‐Grafted Silicon Nanostructures