Area of research
Oncology · Immunology
Research interest
Research interests include Cytokine Signaling Pathways and Interactions, Immune Cell Function and Interaction, interferon and immune responses, and Platelet Disorders and Treatments.
The transcriptional co-repressor Runx1t1 is essential for MYCN-driven neuroblastoma tumorigenesis
In vivo clonal tracking reveals evidence of haemangioblast and haematomesoblast contribution to yolk sac haematopoiesis.
BAF complex-mediated chromatin relaxation is required for establishment of X chromosome inactivation.
Chromosomes distribute randomly to, but not within, human neutrophil nuclear lobes.
Proteomic analyses reveal that immune integrins are major targets for regulation by Membrane-Associated Ring-CH (MARCH) proteins MARCH2, 3, 4 and 9.
Dissecting the molecular control of Interleukin 6 signaling using the M1 cell line.
Membrane budding is a major mechanism of in vivo platelet biogenesis.
Phylotranscriptomics resolves phylogeny of the Heliozelidae (Adeloidea: Lepidoptera) and suggests a Late Cretaceous origin in Australia
Haemopedia RNA-seq: a database of gene expression during haematopoiesis in mice and humans.
Membrane-associated RING-CH (MARCH) proteins down-regulate cell surface expression of the interleukin-6 receptor alpha chain (IL6Rα).
The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism
The magnitude of acute hepatitis is more limited by regulation of cytokine signalling than apoptosis of liver-infiltrating effector CD8 T cells (P4174)