Area of research
Surgery · Oncology
Research interest
Research interests include Pancreatic function and diabetes, Pancreatic and Hepatic Oncology Research, Diabetes and associated disorders, and Diabetes Management and Research.
Engineering synthetic suppressor T cells that execute locally targeted immunoprotective programs
Sox9 regulates alternative splicing and pancreatic beta cell function
Species-specific roles for the MAFA and MAFB transcription factors in regulating islet β cell identity
Stem Cell-Based Clinical Trials for Diabetes Mellitus
Selective deletion of human leukocyte antigens protects stem cell-derived islets from immune rejection
Mutations and variants of ONECUT1 in diabetes
Single-cell transcriptome analysis defines heterogeneity of the murine pancreatic ductal tree
Emerging routes to the generation of functional β-cells for diabetes mellitus cell therapy
Loss of the transcription factor MAFB limits β-cell derivation from human PSCs
Recapitulating endocrine cell clustering in culture promotes maturation of human stem-cell-derived β cells
mTORC1-to-AMPK switching underlies β cell metabolic plasticity during maturation and diabetes
Lipid Droplet Accumulation in Human Pancreatic Islets Is Dependent On Both Donor Age and Health
Stem Cell Therapies for Treating Diabetes: Progress and Remaining Challenges
Replication confers β cell immaturity
The BRG1/SOX9 axis is critical for acinar cell–derived pancreatic tumorigenesis
Mitigating Ischemic Injury of Stem Cell-Derived Insulin-Producing Cells after Transplant
Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression
Human islets contain four distinct subtypes of β cells
Human pancreatic beta-like cells converted from fibroblasts
Life and death of β cells in Type 1 diabetes: A comprehensive review
Rebranding asymptomatic type 1 diabetes: the case for autoimmune beta cell disorder as a pathological and diagnostic entity
Controlled induction of human pancreatic progenitors produces functional beta‐like cells <i>in vitro</i>
DNA methylation directs functional maturation of pancreatic β cells
Islet formation in mice and men: lessons for the generation of functional insulin-producing β-cells from human pluripotent stem cells
NFATc1 Links EGFR Signaling to Induction of Sox9 Transcription and Acinar–Ductal Transdifferentiation in the Pancreas
Regulation of Cellular Identity in Cancer
β-Cell Insulin Secretion Requires the Ubiquitin Ligase COP1
Human stem cells from single blastomeres reveal pathways of Embryonic or trophoblast fate specification
CDK1 Inhibition Targets the p53-NOXA-MCL1 Axis, Selectively Kills Embryonic Stem Cells, and Prevents Teratoma Formation
The chromatin regulator Brg1 suppresses formation of intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinoma