Area of research
Oncology · Molecular Biology
Research interest
Research interests include Pancreatic and Hepatic Oncology Research, Pancreatic function and diabetes, Epigenetics and DNA Methylation, and FOXO transcription factor regulation.
Oncogenic and tumor-suppressive forces converge on a progenitor niche at the benign-to-malignant transition
α-Ketoglutarate dehydrogenase is a therapeutic vulnerability in acute myeloid leukemia
Concurrent Inhibition of the RAS-MAPK Pathway and PIKfyve Is a Therapeutic Strategy for Pancreatic Cancer
EZH2 inhibition remodels the inflammatory senescence-associated secretory phenotype to potentiate pancreatic cancer immune surveillance
MLL3 regulates the CDKN2A tumor suppressor locus in liver cancer
Ordered and deterministic cancer genome evolution after p53 loss
South-to-north migration preceded the advent of intensive farming in the Maya region
A preclinical platform for assessing antitumor effects and systemic toxicities of cancer drug targets
Ogdh Is a Genetic Vulnerability and Therapeutic Target in Acute Myeloid Leukemia
A gene–environment-induced epigenetic program initiates tumorigenesis
Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer
Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in Pancreatic Cancer
Vitamin B6 Addiction in Acute Myeloid Leukemia
α-Ketoglutarate links p53 to cell fate during tumour suppression
p53 Represses the Mevalonate Pathway to Mediate Tumor Suppression
Arid1a restrains Kras-dependent changes in acinar cell identity
A combinatorial strategy for treating KRAS-mutant lung cancer
Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling
The chromatin regulator Brg1 suppresses formation of intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinoma
Dicer Regulates Differentiation and Viability during Mouse Pancreatic Cancer Initiation
Canonical Wnt Signaling Is Required for Pancreatic Carcinogenesis
Nr5a2 maintains acinar cell differentiation and constrains oncogenic Kras-mediated pancreatic neoplastic initiation
Dormant Cancer Cells Contribute to Residual Disease in a Model of Reversible Pancreatic Cancer
Identification of Sox9-Dependent Acinar-to-Ductal Reprogramming as the Principal Mechanism for Initiation of Pancreatic Ductal Adenocarcinoma
SHF: MEDIUM: Extensible LCF-style Theorem Proving with Dependent Rows
SHF: SMALL: A New Semantics for Type-Level Programming in Haskell
Collaborative Research: FMitF: Track III: Integrating Formal Methods into the Foundational Undergraduate Curriculum
CAREER: Extensibility in Theory and Practice
Energy Exchange, Accommodation, and Reaction Dynamics of Atmospheric Gases with Organic Surfaces
Understanding and Controlling the Ductile-Brittle Transition in High-Strength Martensitic Steel
Workshop on the Limits of Strength in Practice and Theory; Berkeley, CA; March 28-29, 2008
Molecular Beam Studies of Energy Exchange, Accommodation, and Acid/Base Chemistry at the Gas-Solid Interface
CAREER: Reaction Dynamics of Hydrogen Halides on OH-Functionalized Surfaces and Development of Guided-Inquiry Experiments for Analytical Chemistry
Proteoglycans of the Developing Retina
Plastic Deformation Through Thernally Activated Glide