Area of research
Physiology · Hepatology
Research interest
Research interests include Spaceflight effects on biology, Liver physiology and pathology, Single-cell and spatial transcriptomics, and COVID-19 Clinical Research Studies.
Standardized metrics for assessment and reproducibility of imaging-based spatial transcriptomics datasets
The Space Omics and Medical Atlas (SOMA) and international astronaut biobank
Longitudinal multi-omics analysis of host microbiome architecture and immune responses during short-term spaceflight
Distinct clinical outcomes and biological features of specific KRAS mutants in human pancreatic cancer
Molecular and physiological changes in the SpaceX Inspiration4 civilian crew
Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight
A second space age spanning omics, platforms and medicine across orbits
Spaceflight induces changes in gene expression profiles linked to insulin and estrogen
Spatial multi-omics of human skin reveals KRAS and inflammatory responses to spaceflight
Space radiation damage rescued by inhibition of key spaceflight associated miRNAs
Lethal COVID-19 associates with RAAS-induced inflammation for multiple organ damage including mediastinal lymph nodes
A comprehensive SARS-CoV-2 and COVID-19 review, Part 2: host extracellular to systemic effects of SARS-CoV-2 infection
IL-6/STAT3 axis dictates the PNPLA3-mediated susceptibility to non-alcoholic fatty liver disease
Spatial omics technologies at multimodal and single cell/subcellular level
System-wide transcriptome damage and tissue identity loss in COVID-19 patients
CRISPR screening uncovers a central requirement for HHEX in pancreatic lineage commitment and plasticity restriction
The spatial landscape of lung pathology during COVID-19 progression
An optical nanoreporter of endolysosomal lipid accumulation reveals enduring effects of diet on hepatic macrophages in vivo