Area of research
Molecular Biology · Hematology
Research interest
Research interests include Acute Myeloid Leukemia Research, Epigenetics and DNA Methylation, Histone Deacetylase Inhibitors Research, and Spaceflight effects on biology.
Guardians of the Mitochondria: Space Mitochondria 2.0 Systemic Analysis Reveals Bioenergetic Dysregulation Across Species
Global biogeography of airborne viruses in public transit systems and their host interactions
Longitudinal multi-omics analysis of host microbiome architecture and immune responses during short-term spaceflight
Molecular and physiological changes in the SpaceX Inspiration4 civilian crew
EZH2 inhibition enhances T cell immunotherapies by inducing lymphoma immunogenicity and improving T cell function
Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight
A second space age spanning omics, platforms and medicine across orbits
Cosmic kidney disease: an integrated pan-omic, physiological and morphological study into spaceflight-induced renal dysfunction
Single-cell analysis identifies conserved features of immune dysfunction in simulated microgravity and spaceflight
ARID1A orchestrates SWI/SNF-mediated sequential binding of transcription factors with ARID1A loss driving pre-memory B cell fate and lymphomagenesis
Secretome profiling reveals acute changes in oxidative stress, brain homeostasis, and coagulation following short-duration spaceflight
Aging and putative frailty biomarkers are altered by spaceflight
Spatial multi-omics of human skin reveals KRAS and inflammatory responses to spaceflight
SMARCA4 is a haploinsufficient B cell lymphoma tumor suppressor that fine-tunes centrocyte cell fate decisions
Loss of CREBBP and KMT2D cooperate to accelerate lymphomagenesis and shape the lymphoma immune microenvironment
Space radiation damage rescued by inhibition of key spaceflight associated miRNAs
Telomeric RNA (TERRA) increases in response to spaceflight and high-altitude climbing
Lethal COVID-19 associates with RAAS-induced inflammation for multiple organ damage including mediastinal lymph nodes
Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts
IDH2 and TET2 mutations synergize to modulate T Follicular Helper cell functional interaction with the AITL microenvironment
PRMT5 supports multiple oncogenic pathways in mantle cell lymphoma
Distinct and opposite effects of leukemogenic <i>Idh</i> and <i>Tet2</i> mutations in hematopoietic stem and progenitor cells
System-wide transcriptome damage and tissue identity loss in COVID-19 patients
Blocking UBE2N abrogates oncogenic immune signaling in acute myeloid leukemia
The spatial landscape of lung pathology during COVID-19 progression
A global metagenomic map of urban microbiomes and antimicrobial resistance
Chemotherapy Induces Senescence-Like Resilient Cells Capable of Initiating AML Recurrence
Shotgun transcriptome, spatial omics, and isothermal profiling of SARS-CoV-2 infection reveals unique host responses, viral diversification, and drug interactions
A diagnostic host response biosignature for COVID-19 from RNA profiling of nasal swabs and blood
Role of miR-2392 in driving SARS-CoV-2 infection