Area of research
Physiology · Neurology
Research interest
Research interests include Alzheimer's disease research and treatments, Dementia and Cognitive Impairment Research, Amyotrophic Lateral Sclerosis Research, and Parkinson's Disease Mechanisms and Treatments.
Deciphering distinct genetic risk factors for FTLD-TDP pathological subtypes via whole-genome sequencing
Genome sequence analyses identify novel risk loci for multiple system atrophy
MAPT H2 haplotype and risk of Pick's disease in the Pick's disease International Consortium: a genetic association study
Genome-wide structural variant analysis identifies risk loci for non-Alzheimer’s dementias
The status of digital pathology and associated infrastructure within Alzheimer’s Disease Centers
Ancestry‐related differences in chromatin accessibility and gene expression of <i>APOE</i> ε4 are associated with Alzheimer's disease risk
Neuropathologic Changes of Alzheimer’s Disease and Related Dementias: Relevance to Future Prevention
LATE-NC staging in routine neuropathologic diagnosis: an update
Frequency of LATE neuropathologic change across the spectrum of Alzheimer’s disease neuropathology: combined data from 13 community-based or population-based autopsy cohorts
Interpretable deep learning translation of GWAS and multi-omics findings to identify pathobiology and drug repurposing in Alzheimer’s disease
Interpretable deep learning of myelin histopathology in age-related cognitive impairment
Differential Vulnerability of Hippocampal Subfields in Primary Age-Related Tauopathy and Chronic Traumatic Encephalopathy
Common Variants Near <scp>ZIC1</scp> and <scp>ZIC4</scp> in Autopsy‐Confirmed Multiple System Atrophy
Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture
Reducing acetylated tau is neuroprotective in brain injury
Neuropathological fingerprints of survival, atrophy and language in primary progressive aphasia
Genome-wide association study and functional validation implicates JADE1 in tauopathy
Genome-wide association study and functional validation implicates JADE1 in tauopathy
Early Selective Vulnerability of the CA2 Hippocampal Subfield in Primary Age-Related Tauopathy
Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report
Concepts for brain aging: resistance, resilience, reserve, and compensation
P1‐111: RESISTANCE, RESERVE, AND RESILIENCE: SYSTEMS THAT DEFEND AGAINST AGE‐RELATED COGNITIVE DECLINE—OBSERVATIONS FROM THE HONOLULU‐ASIA AGING STUDY (HAAS)
P3‐064: COGNITIVE DECLINE TRAJECTORIES IN AUTOPSIED DEMENTIA PARTICIPANTS OF THE NUN STUDY (NS) AND THE HONOLULU‐ASIA AGING STUDY (HAAS): RELATIONSHIPS TO AGE, PREMORBID COGNITIVE TEST SCORES, EDUCATION, APOE4, AND NEUROPATHOLOGIC BURDEN
P2‐067: WHAT WOULD BE THE LIKELY IMPACT OF AN INTERVENTION THAT SUCCESSFULLY PREVENTED NEOCORTICAL ACCUMULATION OF NEURITIC AMYLOID PLAQUES AND A HIGH BRAAK STAGE? THOUGHT EXPERIMENTS USING DATA FROM THE NUN STUDY (NS) AND THE HONOLULU‐ASIA AGING STUDY
Psychosis in Spinocerebellar Ataxias: a Case Series and Study of Tyrosine Hydroxylase in Substantia Nigra