Area of research
Pathology and Forensic Medicine · Cancer Research
Research interest
Research interests include Genetic factors in colorectal cancer, Cancer Genomics and Diagnostics, Colorectal Cancer Treatments and Studies, and Genetic Associations and Epidemiology.
Fine-mapping analysis including over 254,000 East Asian and European descendants identifies 136 putative colorectal cancer susceptibility genes
Transformer-based biomarker prediction from colorectal cancer histology: A large-scale multicentric study
Author Correction: Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries
Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries
Germline MBD4 deficiency causes a multi-tumor predisposition syndrome
Mortality Among Adults With Cancer Undergoing Chemotherapy or Immunotherapy and Infected With COVID-19
Germline genetic variation and predicting immune checkpoint inhibitor induced toxicity
GWAS meta-analysis of 16 790 patients with Barrett’s oesophagus and oesophageal adenocarcinoma identifies 16 novel genetic risk loci and provides insights into disease aetiology beyond the single marker level
eQTL Set–Based Association Analysis Identifies Novel Susceptibility Loci for Barrett Esophagus and Esophageal Adenocarcinoma
Multitrait genetic association analysis identifies 50 new risk loci for gastro-oesophageal reflux, seven new loci for Barrett’s oesophagus and provides insights into clinical heterogeneity in reflux diagnosis
A comprehensive re-assessment of the association between vitamin D and cancer susceptibility using Mendelian randomization
COVID-19 mortality in patients with cancer on chemotherapy or other anticancer treatments: a prospective cohort study
COVID-19 prevalence and mortality in patients with cancer and the effect of primary tumour subtype and patient demographics: a prospective cohort study
Mendelian randomization analyses suggest a role for cholesterol in the development of endometrial cancer
Germline variation in the insulin-like growth factor pathway and risk of Barrett’s esophagus and esophageal adenocarcinoma
Association analyses identify 31 new risk loci for colorectal cancer susceptibility
Modifiable pathways for colorectal cancer: a mendelian randomisation analysis
A Summary of the Fight Colorectal Cancer Working Meeting: Exploring Risk Factors and Etiology of Sporadic Early-Age Onset Colorectal Cancer
Evaluating the role of ENOSF1 and TYMS variants as predictors in fluoropyrimidine-related toxicities: An IPD meta-analysis
No Association Between Vitamin D Status and Risk of Barrett's Esophagus or Esophageal Adenocarcinoma: A Mendelian Randomization Study
Identification of nine new susceptibility loci for endometrial cancer
The evolutionary landscape of colorectal tumorigenesis
Somatic <i>POLE</i> exonuclease domain mutations are early events in sporadic endometrial and colorectal carcinogenesis, determining driver mutational landscape, clonal neoantigen burden and immune response
Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis
Five endometrial cancer risk loci identified through genome-wide association analysis
Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer
Germline variation in inflammation-related pathways and risk of Barrett's oesophagus and oesophageal adenocarcinoma
Correspondence: SEMA4A variation and risk of colorectal cancer
Clinical relevance of DPYD variants c.1679T>G, c.1236G>A/HapB3, and c.1601G>A as predictors of severe fluoropyrimidine-associated toxicity: a systematic review and meta-analysis of individual patient data
Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1