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James McCloskey

Hackensack University Medical Center ·
Area of research
Hematology · Genetics
Research interest
Research interests include Acute Myeloid Leukemia Research, Chronic Myeloid Leukemia Treatments, Chronic Lymphocytic Leukemia Research, and Acute Lymphoblastic Leukemia research.
h-index
19
citations
2,111
works
157
NIH funding
primary concept
Medicine
email

Recent publications

Ziftomenib in Relapsed or Refractory <i>NPM1</i> -Mutated AML
Journal of Clinical Oncology 2025cited by 16position: middledoi
Ziftomenib in combination with venetoclax and azacitidine in relapsed/refractory NPM1-m or KMT2A-r acute myeloid leukemia: Updated phase 1a/b safety and clinical activity results from KOMET-007
Blood 2025cited by 5position: middledoi
Preliminary data from the Phase I/II study of nuvisertib, an oral investigational selective PIM1 inhibitor, in combination with momelotinib showed clinical responses in patients with relapsed/refractory myelofibrosis
Blood 2025cited by 2position: middledoi
Ponatinib vs Imatinib in Frontline Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia
JAMA 2024cited by 108position: middledoi
R289, a Dual Irak 1/4 Inhibitor, in Patients with Relapsed/Refractory (R/R) Lower-Risk Myelodysplastic Syndrome (LR-MDS): Initial Results from a Phase 1b Study
Blood 2024cited by 7position: middledoi
Oral decitabine–cedazuridine versus intravenous decitabine for myelodysplastic syndromes and chronic myelomonocytic leukaemia (ASCERTAIN): a registrational, randomised, crossover, pharmacokinetics, phase 3 study
The Lancet Haematology 2023cited by 80position: middledoi
Transform-1: A Randomized, Double-Blind, Placebo-Controlled, Multicenter, International Phase 3 Study of Navitoclax in Combination with Ruxolitinib Versus Ruxolitinib Plus Placebo in Patients with Untreated Myelofibrosis
Blood 2023cited by 37position: middledoi
First report of PhALLCON: A phase 3 study comparing ponatinib (pon) vs imatinib (im) in newly diagnosed patients with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL).
Journal of Clinical Oncology 2023cited by 18position: middledoi
Venetoclax Plus Gilteritinib for <i>FLT3</i>-Mutated Relapsed/Refractory Acute Myeloid Leukemia
Journal of Clinical Oncology 2022cited by 184position: middledoi
Ponatinib dose-ranging study in chronic-phase chronic myeloid leukemia: a randomized, open-label phase 2 clinical trial
Blood 2021cited by 192position: middledoi
Venetoclax in Combination with Gilteritinib Demonstrates Molecular Clearance of <i>FLT3</i> mutation in Relapsed/Refractory <i>FLT3</i>-Mutated Acute Myeloid Leukemia
Blood 2021cited by 11position: middledoi
Ivosidenib or enasidenib combined with intensive chemotherapy in patients with newly diagnosed AML: a phase 1 study
Blood 2020cited by 232position: middledoi
Oral cedazuridine/decitabine for MDS and CMML: a phase 2 pharmacokinetic/pharmacodynamic randomized crossover study
Blood 2020cited by 210position: middledoi
Loncastuximab tesirine, an anti-CD19 antibody-drug conjugate, in relapsed/refractory B-cell acute lymphoblastic leukemia
Blood Advances 2020cited by 56position: middledoi
Efficacy and Safety of Venetoclax in Combination with Gilteritinib for Relapsed/Refractory <i>FLT3</i>-Mutated Acute Myeloid Leukemia in the Expansion Cohort of a Phase 1b Study
Blood 2020cited by 27position: middledoi
Clinical Efficacy and Safety of Oral Decitabine/Cedazuridine in 133 Patients with Myelodysplastic Syndromes (MDS) and Chronic Myelomonocytic Leukemia (CMML)
Blood 2020cited by 21position: middledoi
Pharmacokinetic Exposure Equivalence and Preliminary Efficacy and Safety from a Randomized Cross over Phase 3 Study (ASCERTAIN study) of an Oral Hypomethylating Agent ASTX727 (cedazuridine/decitabine) Compared to IV Decitabine
Blood 2019cited by 60position: middledoi
Phase Ib Study of Glasdegib, a Hedgehog Pathway Inhibitor, in Combination with Standard Chemotherapy in Patients with AML or High-Risk MDS
Clinical Cancer Research 2018cited by 107position: middledoi
Ivosidenib or Enasidenib Combined with Induction and Consolidation Chemotherapy in Patients with Newly Diagnosed AML with an IDH1 or IDH2 Mutation Is Safe, Effective, and Leads to MRD-Negative Complete Remissions
Blood 2018cited by 61position: middledoi

Grants

Mass Spectrometric Study of Cytokinins and Related Constituents
NSF7807474$4,0511978–1980PIRePORTER
Structure Determination By Mass Spectrometry of Modified Nucleosides in Transfer Ribonucleic Acid
NSF7422813$3,0001975–1977PIRePORTER
Structure of Nucleosides in Transfer Ribonucleic Acid
NSF7420123$61,0001974–1977PIRePORTER

Frequent collaborators

Hagop M. Kantarjian · The University of Texas MD Anderson Cancer Center5 papers (2018–2024)Gary J. Schiller · APLA Health4 papers (2020–2024)Joseph Maly · Norton Healthcare4 papers (2019–2022)Jessica K. Altman · Northwestern University3 papers (2020–2022)Naval Daver · The University of Texas MD Anderson Cancer Center3 papers (2020–2022)Alexander E. Perl · Hospital of the University of Pennsylvania3 papers (2020–2022)Michael R. Savona · Vanderbilt University3 papers (2018–2020)Philippe Rousselot · Infectious Disease Models and Innovative Therapies3 papers (2021–2024)Guillermo Garcia‐Manero · Cancer Clinic3 papers (2019–2024)Terrence Bradley · University of Miami3 papers (2020–2022)Ellen K. Ritchie · Cornell University3 papers (2020–2022)Kiran Naqvi · Center for Children3 papers (2021–2024)Mark R. Litzow · Mayo Clinic3 papers (2020–2022)Mark J. Levis · University of Turin3 papers (2020–2022)Catherine C. Smith · University of San Francisco3 papers (2020–2022)Ramón V. Tiu · Eli Lilly (United States)3 papers (2020–2022)Gail J. Roboz · Cornell University2 papers (2019–2020)Jörge E. Cortes · Cecil College2 papers (2018–2021)Satya R. Siddani · AbbVie (United States)2 papers (2021–2022)Jessica Leonard · Yale University2 papers (2023–2024)